Evidence map›Paper›PMID 33788795›Full record

ArticleEpidemiology (Cambridge, Mass.)2021

Long-term Exposure to PM2.5 and Mortality for the Older Population: Effect Modification by Residential Greenness.

Ji-Young Son, M Benjamin Sabath, Kevin J Lane, Marie Lynn Miranda, Francesca Dominici, Qian Di, Joel Schwartz, Michelle L Bell

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Ambient Fine Particulate Matter, Residential Greenness, and Childhood Cancer Risk by Trimester of Exposure in Minnesota 2000 to 2014: A Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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  9. Weekly prenatal PMEnvironmental research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ji-Young SonFrom the School of the Environment, Yale University, New Haven, CT.
M Benjamin SabathDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
Kevin J LaneSchool of Public Health, Boston University, Boston, MA.
Marie Lynn MirandaDepartment of Statistics, Rice University, Houston, TX.
Francesca DominiciDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.
Qian DiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA.
Michelle L BellFrom the School of the Environment, Yale University, New Haven, CT.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Environmental Health Disparities in an Older PopulationR01MD012769 · NIMHD · YALE UNIVERSITY · PI BELL, MICHELLE L · 2017 to 2021
$3.9M
EPA R835871NCATS NIH HHS UL1 TR001863NIMHD NIH HHS R01 MD012769
6 · The paper itself

Abstract

backgroundAlthough many studies demonstrated reduced mortality risk with higher greenness, few studies examined the modifying effect of greenness on air pollution-health associations. We evaluated residential greenness as an effect modifier of the association between long-term exposure to fine particles (PM2.5) and mortality.

methodsWe used data from all Medicare beneficiaries in North Carolina (NC) and Michigan (MI) (2001-2016). We estimated annual PM2.5 averages using ensemble prediction models. We estimated mortality risk per 1 μg/m3 increase using Cox proportional hazards modeling, controlling for demographics, Medicaid eligibility, and area-level covariates. We investigated health disparities by greenness using the Normalized Difference Vegetation Index with measures of urbanicity and socioeconomic status.

resultsPM2.5 was positively associated with mortality risk. Hazard ratios (HRs) were 1.12 (95% confidence interval (CI) = 1.12 to 1.13) for NC and 1.01 (95% CI = 1.00 to 1.01) for MI. HRs were higher for rural than urban areas. Within each category of urbanicity, HRs were generally higher in less green areas. For combined disparities, HRs were higher in low greenness or low SES areas, regardless of the other factor. HRs were lowest in high-greenness and high-SES areas for both states.

conclusionsIn our study, those in low SES and high-greenness areas had lower associations between PM2.5 and mortality than those in low SES and low greenness areas. Multiple aspects of disparity factors and their interactions may affect health disparities from air pollution exposures. Findings should be considered in light of uncertainties, such as our use of modeled PM2.5 data, and warrant further investigation.

Indexed as

Air PollutantsAir PollutionAgedEnvironmental ExposureHumansMedicareMichiganNorth CarolinaParticulate MatterUnited StatesAir PollutantsParticulate Matter

Identifiers

PMID33788795
PMCPMC8159868

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.