Evidence map›Paper›PMID 33788620›Full record

ArticleJournal of neurophysiology2021

Sodium sensitivity of K

Richard Gray, Daniel Johnston

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. KNeurobiology of disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Richard GrayCenter for Learning and Memory, Department of Neuroscience, University of Texas at Austin, Austin, Texas.ORCID 0000-0002-5890-1819
Daniel JohnstonCenter for Learning and Memory, Department of Neuroscience, University of Texas at Austin, Austin, Texas.
The University of Texas at Austin · US

Funding

Cellular Information Processing in the HippocampusR01NS084473 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI JOHNSTON, DANIEL · 2013 to 2017
$1.7M
NINDS NIH HHS R01 NS084473
6 · The paper itself

Abstract

Potassium channels play an important role regulating transmembrane electrical activity in essentially all cell types. We were especially interested in those that determine the intrinsic electrical properties of mammalian central neurons. Over 30 different potassium channels have been molecularly identified in brain neurons, but there often is not a clear distinction between molecular structure and the function of a particular channel in the cell. Using patch-clamp methods to search for single potassium channels in excised inside-out (ISO) somatic patches with symmetrical potassium, we found that nearly all patches contained non-voltage-inactivating channels with a single-channel conductance of 100-200 pS. This conductance range is consistent with the family of sodium-activated potassium channels (Slo2.1, Slo2.2, or collectively, K

Indexed as

AnimalsCA1 Region, HippocampalCardiotonic AgentsMaleMiceNerve Tissue ProteinsOuabainPatch-Clamp TechniquesPotassium Channels, Sodium-ActivatedPyramidal CellsSodiumCardiotonic AgentsNerve Tissue ProteinsOuabainPotassium Channels, Sodium-ActivatedSlo2 protein, mouseSodiummouse hippocampusouabainsingle channelssodium-activated potassium

Identifiers

PMID33788620
PMCPMC8356759
OpenAlexW3144586246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.