Evidence map›Paper›PMID 33788596›Full record

ArticleJCO global oncology2021

Evaluation of the Pediatric Neuro-Oncology Resources Available in Chile.

Mohammad H Abu-Arja, Nicolás Rojas Del Río, Andres Morales La Madrid, Alvaro Lassaletta, Scott L Coven, Rosa Moreno, Miguel Valero, Veronica Perez, Felipe Espinoza, Eduardo Fernandez and 11 more

Open access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 19 institutions in 5 countries.

Mohammad H Abu-ArjaDepartment of Pediatrics, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY.ORCID 0000-0003-4606-2269
Nicolás Rojas Del RíoDepartment of Pediatrics, Division of Hematology Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Andres Morales La MadridDepartment of Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.
Alvaro LassalettaThe Pediatric Oncology, Hematology and Stem Cell Transplant Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.ORCID 0000-0003-2881-1473
Scott L CovenDivision of Pediatric Hematology-Oncology, Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, IN.ORCID 0000-0003-2763-7928
Rosa MorenoDepartment of Pediatrics, Pediatría Hospital Dr. Sótero del Río, Puente Alto, Chile.
Miguel ValeroDepartment of Pediatrics, Hospital Carlos van Buren, Valparaíso, Chile.
Veronica PerezDepartment of Pediatrics, Hospital San Juan de Dios, Santiago, Chile.
Felipe EspinozaDepartment of Pediatrics, San Borja Arriaran Clinic Hospital, Santiago, Chile.
Eduardo FernandezDepartment of Pediatrics, Hospital Clínico Regional Dr. Guillermo Grant Benavente de Concepción, Concepción, Chile.
José SantanderDepartment of Pediatrics, Clinica Davila, Recoleta, Chile.ORCID 0000-0002-9435-8577
Juan TordecillaDepartment of Pediatrics, Clinica Santa Maria, Providencia, Chile.
Veronica OyarceDepartment of Pediatrics, Dr. Exequiel González Cortés Hospital, San Miguel, Chile.
Katherine KoppDepartment of Pediatrics, Dr. Luis Calvo Mackenna Hospital, Santiago, Chile.
Ute BartelsDepartment of Hematology Oncology, Hospital for Sick Children, Toronto, Canada.
Ibrahim QaddoumiGlobal Pediatric Medicine Department, St Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-6645-4895
Jonathan L FinlayDivision of Hematology, Oncology, Blood and Marrow Transplant, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH.
Adrián CáceresNeurosurgery Unit, Hospital Nacional de Niños Carlos Sáenz Herrera, San José, Costa Rica.ORCID 0000-0003-2337-2168
Mauricio ReyesDepartment of Radiation Oncology, Instituto Nacional del Cáncer, Santiago, Chile.
Ximena EspinozaDepartment of Pediatrics, The Hematology Oncology Unit, Hospital de Niños Dr. Roberto del Río, Santiago, Chile.
Diana S OsorioDivision of Hematology, Oncology, Blood and Marrow Transplant, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH.
Nationwide Children's Hospital · USClínica Dávila · CLClinica Santa Maria · CLComplejo Asistencial Sótero del Río · CLHospital Carlos Van Buren · CLHospital for Sick Children · CAHospital Infantil Universitario Niño Jesús · ESHospital Luis Calvo Mackenna · CLHospital Nacional de Niños · CRHospital Regional de Concepción · CLHospital Roberto del Rio · CLHospital San Borja Arriarán · CLHospital San Juan de Dios · CLHospital Sant Joan de Déu Barcelona · ESInstituto Nacional del Cáncer · CLNewYork–Presbyterian Brooklyn Methodist Hospital · USPontificia Universidad Católica de Chile · CLRiley Hospital for Children · USSt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePediatric neuro-oncology resources are mostly unknown in Chile. We report the human and material resources available in Chilean hospitals providing pediatric neuro-oncology services.

methodsA cross-sectional survey was distributed to 17 hospitals providing pediatric neuro-oncology services (Programa Infantil Nacional de Drogas Antineoplásicas [PINDA] hospitals, 11; private, 6).

resultsResponse rate was 71% (PINDA, 8; private, 4). Pediatric neuro-oncology services were mainly provided within general hospitals (67%). Registries for pediatric CNS tumors and chemotherapy-related toxicities were available in 100% and 67% of hospitals, respectively. CNS tumors were treated by pediatric oncologists in 92% of hospitals; none were formally trained in neuro-oncology. The most used treatment protocols were the national PINDA protocols. All WHO essential medicines for childhood cancer were available in more than 80% of the hospitals except for gemcitabine, oxaliplatin, paclitaxel, and procarbazine. The median number of pediatric neurosurgeons per hospital was two (range, 2-6). General neuroradiologists were available in 83% of the centers. Pathology specimens were sent to neuropathologists (58%), adult pathologists (25%), and pediatric pathologists (17%). Intensity-modulated radiotherapy, conformal radiotherapy, and cobalt radiotherapy were used by 67%, 58%, and 42% of hospitals, respectively. Only one private hospital performed autologous hematopoietic cell transplant for children with CNS tumors.

conclusionA wide range of up-to-date treatment modalities are available for children with CNS tumors. Our survey highlights future directions to improve the pediatric neuro-oncology services available in Chile such as the expansion of multidisciplinary clinics, palliative care services, long-term cancer survivorship programs, dedicated clinical research support teams, establishing standardized mechanism for sending pathologic specimen for second opinion to international specialized centers, and establishing specialized neuro-oncology training program.

Indexed as

Central Nervous System NeoplasmsHematopoietic Stem Cell TransplantationChildChileCross-Sectional StudiesHumansMedical Oncology

Identifiers

PMID33788596
PMCPMC8081533
OpenAlexW3149223227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.