Evidence map›Paper›PMID 33788417›Full record

ArticlePediatric blood & cancer2021

Novel risk factors for glucarpidase use in pediatric acute lymphoblastic leukemia: Hispanic ethnicity, age, and the ABCC4 gene.

Mark C Zobeck, M Brooke Bernhardt, Kala Y Kamdar, Karen R Rabin, Philip J Lupo, Michael E Scheurer

Open access · greenAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mark C ZobeckBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0003-0997-906X
M Brooke BernhardtBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0002-9612-3624
Kala Y KamdarBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0003-0892-7727
Karen R RabinBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0002-4081-8195
Philip J LupoBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0003-0978-5863
Michael E ScheurerBaylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.ORCID 0000-0002-8379-6088
Baylor College of Medicine · US

Funding

MEDICAL GENETICS RESEARCH FELLOWSHIP PROGRAMT32GM007526 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Brendan Lee · 1985 to 2026
$11.4M
NIGMS NIH HHS T32 GM007526
6 · The paper itself

Abstract

backgroundCarboxypeptidase G PROCEDURE: Cases who received CPDG

resultsWe identified 423 patients who received 1592 doses of MTX. Of the 18 patients who received CPDG

conclusionWe demonstrated that demographic characteristics, including Hispanic ethnicity and age, are associated with CPDG

Indexed as

Precursor Cell Lymphoblastic Leukemia-LymphomaAge FactorsATP-Binding Cassette, Sub-Family C ProteinsBayes TheoremChildgamma-Glutamyl HydrolaseHispanic or LatinoHumansMethotrexateRecombinant ProteinsRisk FactorsABCC4 protein, humanATP-Binding Cassette, Sub-Family C Proteinsgamma-Glutamyl HydrolaseglucarpidaseMethotrexateRecombinant ProteinsancestrygeneticsglucarpidaseHispanic ethnicitymethotrexatepediatric acute lymphoblastic leukemia

Identifiers

PMID33788417
PMCPMC8238882
OpenAlexW3146121726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.