Evidence map›Paper›PMID 33788107›Full record

ArticleBulletin of experimental biology and medicine2021

Effect of Mild Traumatic Brain Injury on Behavioral Reactions and Neocortical Morphology in Rats.

N G Plekhova, I V Radkov, S V Zinoviev, I V Dyuizen, A N Baryshev, V B Shumatov

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

N G PlekhovaPacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia. pl_nat@hotmail.com.
I V RadkovPacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia.
S V ZinovievPacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia.
I V DyuizenA. V. Zhirmunsky Institute of Marine Biology, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
A N BaryshevA. V. Zhirmunsky Institute of Marine Biology, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
V B ShumatovPacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia.
Vladivostok State Medical University · RUA.V. Zhirmunsky National Scientific Center of Marine Biology Far Eastern Branch of the Russian Academy of Sciences · RUMinistry of Health of the Russian Federation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The original weight-drop model was employed to examine the effect of mild traumatic brain injury (TBI) on behavioral phenotype and neocortical morphology in rats. The neurological examination of rats with moderate TBI revealed the focal symptoms corresponding to pronounced neurological disorders, whereas in rats after mild TBI, there were only minor coordination disorders. On day 7 after injury, the rats with mild TBI demonstrated enhanced anxiety assessed by conditioned passive avoidance response. The morphometric analysis of the brain tissues revealed narrowing of the capillaries and increased score of hyperchromic neocortical neurons, which attested to cerebral hypoxia. The manifestations of mild TBI in original rat model demonstrated a close similarity to the symptoms of TBI in humans.

Indexed as

AnimalsBrainBrain ConcussionBrain InjuriesBrain Injuries, TraumaticDisease Models, AnimalMaleNeocortexNeuronsRatsRats, Wistarbehavioral phenotypeexperimental modelneocortexratstraumatic brain injury

Identifiers

PMID33788107
OpenAlexW3147557659

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.