ArticleDigestive diseases and sciences2022
Visceral Adipose Tissue and Non-alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes.
Article in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Associations between adiposity indices and liver steatosis and stiffness assessed by two-dimensional shear wave elastography in patients with type 2 diabetes mellitus: a cross-sectional study.BMC endocrine disorders · 2026Article
- Metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus in Tanzania: prevalence and predictors.BMC endocrine disorders · 2026Article
- Metabolic Dysfunction-associated Steatotic Liver Disease Alters Fatty Acid Profiles in the Liver and Adipose Tissue.The Journal of clinical endocrinology and metabolism · 2025Article
- Adipose tissue-targeted drug delivery for treating obesity: current opportunities and challenges.Drug delivery · 2025Review
- Platelet-derived growth factor receptor-β as a non-invasive biomarker for liver fibrosis prediction in Egyptian diabetic patients with metabolic-associated fatty liver disease.BMC gastroenterology · 2025Article
- The effect of aldafermin expressing-Escherichia coli Nissle 1917 along with dietary change on visceral adipose tissue in MASLD mouse model.International journal of obesity (2005) · 2025Article
- Aggregate index of systemic inflammation tied to increased fatty liver disease risk: insights from NHANES data.BMC gastroenterology · 2025Article
- DXA-derived visceral adipose tissue reference values and metabolic syndrome risk threshold in an Algerian adult population.PloS one · 2025Article
- Regional fat distribution and hepatic fibrosis and steatosis severity in patients with nonalcoholic fatty liver disease and type 2 diabetes.Obesity science & practice · 2024Article
- The Link between Abdominal Obesity Indices and the Progression of Liver Fibrosis: Insights from a Population-Based Study.Nutrients · 2024Article
- Association between type 2 diabetes mellitus and body composition based on MRI fat fraction mapping.Frontiers in public health · 2024Article
- Association of body fat and muscle tissue parameters with fatty liver disease identified by ultrasound.Lipids in health and disease · 2023Article
- LEARN algorithm: a novel option for predicting non-alcoholic steatohepatitis.Hepatobiliary surgery and nutrition · 2023Article
- Relationship of liver fat content with systemic metabolism and chronic complications in patients with type 2 diabetes mellitus.Lipids in health and disease · 2023Article
- Obesity-Induced Hepatic Steatosis Is Partly Mediated by Visceral Fat Accumulation in Subjects with Overweight/Obesity: A Cross-Sectional Study.Obesity facts · 2023Article
- Relationship between body composition and bone mineral density in postmenopausal women with type 2 diabetes mellitus.BMC musculoskeletal disorders · 2022Article
- Increased Adipose Tissue Indices of Androgen Catabolism and Aromatization in Women With Metabolic Dysfunction.The Journal of clinical endocrinology and metabolism · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the association of visceral adipose tissue (VAT) area and non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM).
methodsThis was a cross-sectional study comprising 100 patients with T2DM and 100 non-T2DM individuals, matched for age, sex, and body mass index (BMI). Transient elastography was used to assess hepatic steatosis and liver stiffness measurements (LSM). Controlled attenuation parameter (CAP) was used to quantify hepatic steatosis. To distinguish grades of hepatic steatosis, cutoff values were as follows: S1 ≥ 302, S2 ≥ 331, and S3 ≥ 337 dB/m. Moreover, VAT area was measured by dual-energy X-ray absorptiometry in accordance with validated protocols.
resultsCAP score was significantly higher in participants with T2DM (294.61 ± 3.82 vs. 269.86 ± 3.86 dB/ m; P < 0.001). Furthermore, 42% of participants with T2DM had hepatic steatosis (S > S1: 302 dB/m), while this figure was 26% in non-T2DM group (P < 0.003). The mean liver stiffness measurement was also significantly higher in patients with T2DM (5.53 vs. 4.79 kPa; P < 0.001). VAT area was greater in patients with T2DM compared to non-T2DM individuals: 163.79 ± 47.98 cm
conclusionVAT area is a major determinant of the severity of hepatic steatosis and liver stiffness in patient with T2DM.
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