Evidence map›Paper›PMID 33788043›Full record

ArticleEJNMMI physics2021

Tissue dose estimation after extravasation of

Perrine Tylski, Géraldine Pina-Jomir, Claire Bournaud-Salinas, Patrice Jalade

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07174089 (New AI-based Technologies for Even Safer and More Precise Nuclear Medicine), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07174089 recruitingnot on this map

New AI-based Technologies for Even Safer and More Precise Nuclear Medicine

TypeobservationalSponsorAzienda USL Reggio Emilia - IRCCSRan2021 to 2026Enrolled1,500ConditionsPatients Undergoing PET/CT Investigation or Nuclear Medicine TherapyArmsRadEye SPRD-ER device: spectrometric radiation detector capable of detecting gamma radiation.
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Extravasation Frequency of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  4. Article
  5. Review
  6. Extravasation of Diagnostic Radiopharmaceuticals: A Wolf in Sheep's Clothing?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Perrine TylskiService de Physique Médicale et Radioprotection, Hospices Civils de Lyon, Lyon, France. perrine.tylski@chu-lyon.fr.ORCID http://orcid.org/0000-0001-8974-6930
Géraldine Pina-JomirService de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Lyon, France.
Claire Bournaud-SalinasService de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Lyon, France.
Patrice JaladeService de Physique Médicale et Radioprotection, Hospices Civils de Lyon, Lyon, France.
Hospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtravasation of radiopharmaceuticals used for vectorized internal radiotherapy can lead to severe tissue damage (van der Pol et al., Eur J Nucl Med Mol Imaging 44:1234-1243, 2017). Clinical management of these extravasations requires the preliminary estimation of the dose distribution in the extravasation area. Data are scarce regarding the dose estimation in the literature. This work presents a methodology for estimating the dose distribution after an extravasation occurred in September 2017, in the arm of a patient during a 7.4-GBq infusion of Lutathera ® (AAA).

methodsA local quantification procedure initially developed for renal dosimetry was used. A calibration factor was determined and verified by phantom study. Extravasation volume of interest and its variation in time were determined using 4 whole body (WB) planar acquisitions performed at 2 h (T

resultsVolumes estimated using 3D threshold were V

conclusionsRapid local dose estimation was permitted thanks to knowledge of the calibration factor determined previous to accidental extravasation. Lutathera® lymphatic drainage was quick in the arm (T

Indexed as

177Lu-DOTATATEDosimetryExtravasation

Identifiers

PMID33788043
PMCPMC8012450
OpenAlexW3140594106

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.