Evidence map›Paper›PMID 33788031›Full record

ArticleSurgical endoscopy2022

Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study.

Andrea Ruzzenente, Andrea Ciangherotti, Luca Aldrighetti, Giuseppe Maria Ettorre, Luciano De Carlis, Alessandro Ferrero, Raffaele Dalla Valle, Giuseppe Tisone, Alfredo Guglielmi, IgoMILS – Sg1 Group

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Andrea RuzzenenteDepartment of Hepatobiliary Surgery, Unit of Hepato-Pancreato-Biliary Surgery, G. B. Rossi Hospital, University of Verona Medical School, Verona, Italy. andrea.ruzzenente@univr.it.ORCID 0000-0001-6911-563X
Andrea CiangherottiDepartment of Hepatobiliary Surgery, Unit of Hepato-Pancreato-Biliary Surgery, G. B. Rossi Hospital, University of Verona Medical School, Verona, Italy.
Luca AldrighettiHepatobiliary Surgery, IRCCS San Raffaele Hospital, Milan, Italy.
Giuseppe Maria EttorreDivision of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Italy.
Luciano De CarlisSurgical and Transplant Department, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Alessandro FerreroDepartment of HPB and Digestive Surgery, Ospedale Mauriziano Umberto I, Turin, Italy.
Raffaele Dalla ValleDepartment of Surgery, Parma University Hospital, Parma, Italy.
Giuseppe TisoneDepartment of Transplant Surgery, Tor Vergata Foundation, Tor Vergata University, Rome, Italy.
Alfredo GuglielmiDepartment of Hepatobiliary Surgery, Unit of Hepato-Pancreato-Biliary Surgery, G. B. Rossi Hospital, University of Verona Medical School, Verona, Italy.
IgoMILS – Sg1 Group
University of Verona · ITUniversity of Rome Tor Vergata · ITVita-Salute San Raffaele University · ITUniversity of Parma · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITIRCCS San Camillo Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group.

methodsPerioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group.

resultsA total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo-Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group.

conclusionsThis multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.

Indexed as

Bile Duct NeoplasmsCarcinoma, HepatocellularLaparoscopyLiver NeoplasmsBile Ducts, IntrahepaticCohort StudiesFeasibility StudiesHepatectomyHumansLength of StayPostoperative ComplicationsPropensity ScoreProspective StudiesRegistriesRetrospective StudiesCaudate lobeMinimally invasive liver surgeryMulti-institutionalPropensity score matched

Identifiers

PMID33788031
PMCPMC8758628
OpenAlexW3145674951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.