Evidence map›Paper›PMID 33787986›Full record

ArticleWorld journal of urology2021

Water vapor therapy (Rezūm) for lower urinary tract symptoms related to benign prostatic hyperplasia: early results from the first Italian multicentric study.

Giampaolo Siena, L Cindolo, G Ferrari, D Maruzzi, G Fasolis, S V Condorelli, F Varvello, F Visalli, S Rabito, S Toso and 5 more

Abstract readMulticenter Study
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Water Vapor Therapy and Zonal Anatomy of the Prostate.International neurourology journal · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Office-Based Procedures for BPH.Current urology reports · 2021
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giampaolo SienaDepartment of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence, Italy. giampaolo.siena@gmail.com.
L CindoloDepartment of Urology, Villa Stuart, Private Hospital, Rome, Italy.
G FerrariDepartment of Urology, Hesperia Hospital, Cure Group, Modena, Italy.
D MaruzziDepartment of Urology, S. Maria Degli Angeli Hospital, Pordenone, Italy.
G FasolisDepartment of Urology, Michele e Pietro Ferrero Hospital, Alba-Bra, Italy.
S V CondorelliDepartment of Urology, Vittorio Emanuele Hospital, Gela, Italy.
F VarvelloDepartment of Urology, Michele e Pietro Ferrero Hospital, Alba-Bra, Italy.
F VisalliDepartment of Urology, S. Maria Degli Angeli Hospital, Pordenone, Italy.
S RabitoDepartment of Urology, Hesperia Hospital, Cure Group, Modena, Italy.
S TosoDepartment of Urology, Hesperia Hospital, Cure Group, Modena, Italy.
S CaroassaiDepartment of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence, Italy.
A MariDepartment of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence, Italy.
L ViolaDepartment of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence, Italy.
B K SomaniUniversity Hospital Southampton NHS Trust, Tremona Road, Southampton, SO16 6YD, Hampshire, UK.
M CariniDepartment of Urology, Careggi Hospital, University of Florence, San Luca Nuovo, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRezūm is the latest developed minimally invasive treatment for benign prostatic hyperplasia (BPH). We aimed to carefully assess the functional outcomes of patients treated with Rezūm for BPH.

methodsWe prospectively followed 135 consecutive patients treated by Rezūm at 5 institutions from June 2019 to August 2020. The International Prostate Symptom Score (IPSS), International Consultation on Incontinence Questionnaire-Short Form (ICIQ-UI SF), the Overactive Bladder Questionnaire-Short Form (OAB-q SF) score, the International Index of Erectile Function (IIEF-5) and questions 9 and 10 to assess ejaculatory dysfunction were recorded. Election criteria were age > 18, no prior prostate interventions, IPSS ≥ 13, post-void residual ≤ 250 mL, prostate volume between 30 and 120 cc.

resultsThe median operative time was 10.5 (IQR 8.7-15) min. All patients were dismissed few hours after surgery with indwelling urinary catheter that was removed after a median of 7 (IQR 7-10) days. A significantly decrease of IPSS from baseline at first (p = 0.001) and third (p < 0.0001) month after surgery was reported. No difference was reported in terms of ICIQ-UI SF score postoperatively. A mild reduction of the OAB-q SF score was reported at 1 month from surgery (p = 0.06) that turned significant at 3 months postoperatively (p < 0.0001). A slight but statistically significant increase of the IIEF-5 score was reported from baseline at 6 months (p = 0.04). Postoperatively, patients reported a significantly decrease of ejaculatory dysfunction after alpha-blocker interruption.

conclusionRezūm treatment is a feasible minimally invasive option for patients with BPH symptoms and showed optimal early functional outcomes.

Indexed as

SteamAgedFollow-Up StudiesHumansHyperthermia, InducedItalyLower Urinary Tract SymptomsMaleMiddle AgedProspective StudiesProstatic HyperplasiaRecovery of FunctionSurveys and QuestionnairesTreatment OutcomeSteamBenign prostatic hyperplasiaMinimally invasiveRezūm

Identifiers

PMID33787986
PMCPMC8010783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.