ArticleAnalytical and bioanalytical chemistry2022
Ag nanoparticles outperform Au nanoparticles for the use as label in electrochemical point-of-care sensors.
Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- A Highly Sensitive Electrochemical Immunosensor Based on Core-Shell SiOFoods (Basel, Switzerland) · 2026Article
- Environmental applications of silver nanoparticles: state-of-the-art review and emerging trends.Beilstein journal of nanotechnology · 2026Review
- Silver Nanoparticles for Biosensing and Drug Delivery: A Mechanical Study on DNA Interaction.Biosensors · 2025Article
- Review
- Signaling strategies of silver nanoparticles in optical and electrochemical biosensors: considering their potential for the point-of-care.Mikrochimica acta · 2023Review
- Smart Nanostructured Materials for SARS-CoV-2 and Variants Prevention, Biosensing and Vaccination.Biosensors · 2022Review
- Freestanding 3D-interconnected carbon nanofibers as high-performance transducers in miniaturized electrochemical sensors.Mikrochimica acta · 2022Article
- New formula of the green synthesised Au@Ag core@shell nanoparticles using propolis extract presented high antibacterial and anticancer activity.AMB Express · 2022Article
- Electroanalytical point-of-care detection of gold standard and emerging cardiac biomarkers for stratification and monitoring in intensive care medicine - a review.Mikrochimica acta · 2022Review
- Electrochemical Synthesis of Zinc Oxide Nanostructures on Flexible Substrate and Application as an Electrochemical Immunoglobulin-G Immunosensor.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrochemical immunosensors enable rapid analyte quantification in small sample volumes, and have been demonstrated to provide high sensitivity and selectivity, simple miniaturization, and easy sensor production strategies. As a point-of-care (POC) format, user-friendliness is equally important and most often not combinable with high sensitivity. As such, we demonstrate here that a sequence of metal oxidation and reduction, followed by stripping via differential pulse voltammetry (DPV), provides lowest limits of detection within a 2-min automatic measurement. In exchanging gold nanoparticles (AuNPs), which dominate in the development of POC sensors, with silver nanoparticles (AgNPs), not only better sensitivity was obtained, but more importantly, the assay protocol could be simplified to match POC requirements. Specifically, we studied both nanoparticles as reporter labels in a sandwich immunoassay with the blood protein biomarker NT-proBNP. For both kinds of nanoparticles, the dose-response curves easily covered the ng∙mL
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