Evidence map›Paper›PMID 33787495›Full record

ArticleeLife2021

Transient kinetic studies of the antiviral

Raushan K Singh, McKenzie Jonely, Evan Leslie, Nick A Rejali, Rodrigo Noriega, Brenda L Bass

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Biochemical and structural basis of Dicer helicase function unveiled by resurrecting ancient proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. eLife · 2024
    Article
  5. bioRxiv : the preprint server for biology · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raushan K SinghDepartment of Biochemistry, University of Utah, Salt Lake City, United States.ORCID 0000-0002-3636-9112
McKenzie JonelyDepartment of Chemistry, University of Utah, Salt Lake City, United States.
Evan LeslieDepartment of Biochemistry, University of Utah, Salt Lake City, United States.
Nick A RejaliDepartment of Pathology, University of Utah, Salt Lake City, United States.ORCID 0000-0001-7210-9425
Rodrigo NoriegaDepartment of Chemistry, University of Utah, Salt Lake City, United States.
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, United States.ORCID 0000-0003-1728-2254
University of Utah · US

Funding

Elucidating roles and mechanisms of double-stranded RNA-mediated pathwaysR35GM141262 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brenda L. Bass · 2021 to 2026
$3.7M
Mechanistic insights into Dicer, a double-stranded RNA processing enzymeR01GM121706 · NIGMS · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 2017 to 2020
$1.5M
NIGMS NIH HHS R01 GM121706NIGMS NIH HHS R35 GM141262
6 · The paper itself

Abstract

Some RIG-I-like receptors (RLRs) discriminate viral and cellular dsRNA by their termini, and

Indexed as

Adenosine TriphosphateAnimalsDrosophila melanogasterDrosophila ProteinsKineticsRibonuclease IIIRNA HelicasesAdenosine TriphosphateDCR-2 protein, DrosophilaDrosophila ProteinsRibonuclease IIIRNA Helicasesbiochemistrychemical biologydicerD. melanogasterdsRNAmolecular biophysicsstructural biologytransient kinetics

Identifiers

PMID33787495
PMCPMC8079148
OpenAlexW3145751560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.