Evidence map›Paper›PMID 33787396›Full record

ArticleInternational journal of stroke : official journal of the International Stroke Society2022

Partitioning risk factors for embolic stroke of undetermined source using exploratory factor analysis.

Jon D Perkins, Naveed Akhtar, Rajvir Singh, Asad Kamran, Saadat Ilyas

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Article in International journal of stroke : official journal of the International Stroke Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jon D PerkinsNeuroscience Institute, Hamad General Hospital, Doha, Qatar.ORCID 0000-0003-2260-0974
Naveed AkhtarNeuroscience Institute, Hamad General Hospital, Doha, Qatar.
Rajvir SinghHeart Hospital, 36977Hamad Medical Corporation, Doha, Qatar.
Asad KamranNeuroscience Institute, Hamad General Hospital, Doha, Qatar.
Saadat IlyasNeuroscience Institute, Hamad General Hospital, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmbolic stroke of undetermined source (ESUS) accounts for up to 25% of strokes. Understanding risk factors associated with ESUS is important in reducing stroke burden worldwide. However, ESUS patients are younger and present with fewer traditional risk factors. Significant global variation in ESUS populations also exists making the clinical picture of this type of stroke unclear. METHODS AND

resultsESUS patients were pair matched for age, sex, and ethnicity with a group of all other strokes (both

conclusionsOur findings support the existence of a unique pattern of risk factors specific to ESUS. We show that LVWMA and corresponding changes in left heart function are a potential source of emboli in these patients. In addition, the clustering of aortic arch atherosclerosis with left heart factors suggests a causal link. Through the application of exploratory factor analysis, this work contributes to a further understanding of stroke mechanisms in ESUS.

Indexed as

Embolic StrokeIntracranial EmbolismStrokeFactor Analysis, StatisticalHumansRisk Factorscardiac dysfunctionESUSexploratory factor analysisrisk modelStroke

Identifiers

PMID33787396
PMCPMC8969073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.