Evidence map›Paper›PMID 33787326›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2021

RSV infection potentiates TRPV

Terri J Harford, Lisa Grove, Fariba Rezaee, Rachel Scheraga, Mitchell A Olman, Giovanni Piedimonte

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
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  7. Article
  8. Update on the Role of β2AR and TRPV1 in Respiratory Diseases.International journal of molecular sciences · 2024
    Review
  9. Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Terri J HarfordDepartment of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.ORCID 0000-0001-6590-0673
Lisa GroveDepartment of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.
Fariba RezaeeDepartment of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.ORCID 0000-0002-7625-3341
Rachel ScheragaDepartment of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.
Mitchell A OlmanDepartment of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio.
Giovanni PiedimonteDepartment of Pediatrics, Tulane School of Medicine, New Orleans, Louisiana.ORCID 0000-0003-1640-1928
Cleveland Clinic Lerner College of Medicine · USTulane University · US

Funding

NEUROGENIC INFLAMMATORY RESPONSE TO RSVR01HL061007 · NHLBI · WEST VIRGINIA UNIVERSITY · PI PIEDIMONTE, GIOVANNI · 1999 to 2022
$7.2M
TRPV4-PI3K Axis Mediates Pulmonary and Cardiac FibrosisR01HL133721 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI OLMAN, MITCHELL ALAN, PRASAD, SATHYAMANGLA V · 2017 to 2020
$2.2M
Mechanisms of Airway Epithelial Barrier Dysfunction by Respiratory Syncytial Virus and Environmental StimuliR01HL148057 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI REZAEE, FARIBA · 2019 to 2023
$2.2M
Profibrotic Mechanisms of the TRPV4-PI3K-gamma Protein ComplexR01HL158746 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI OLMAN, MITCHELL ALAN · 2021 to 2024
$1.6M
Transient Receptor Potential Vanilloid 4 (TRPV4) mediates the host defense and lung injury response to bacterial pneumoniaK08HL133380 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI SCHERAGA, RACHEL GREENBERG · 2016 to 2020
$809k
Cystic Fibrosis Foundation (CF Foundation) PIEDIM16G0HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) K08 HL-133380HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01 HL-061007HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01 HL-133721,R01 HL-11972NHLBI NIH HHS K08 HL133380NHLBI NIH HHS R01 HL061007NHLBI NIH HHS R01 HL133721NHLBI NIH HHS R01 HL148057NHLBI NIH HHS R01 HL158746
6 · The paper itself

Abstract

The transient receptor potential vanilloid 1 (TRPV

Indexed as

AsthmaBronchoconstrictionCalciumChildChild, PreschoolEpithelial CellsEpitheliumHumansIon TransportRespiratory MucosaRespiratory Syncytial Virus InfectionsTRPV Cation ChannelsCalciumTRPV1 protein, humanTRPV Cation Channelsairway hyperreactivitybronchiolitiscalciumendoplasmic reticulumnerve growth factor

Identifiers

PMID33787326
PMCPMC8285623
OpenAlexW3145732720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.