Evidence map›Paper›PMID 33787282›Full record

ArticleJournal of the American Heart Association2021

Sex and Race-Ethnic Disparities in Door-to-CT Time in Acute Ischemic Stroke: The Florida Stroke Registry.

Sai P Polineni, Enmanuel J Perez, Kefeng Wang, Carolina M Gutierrez, Jeffrey Walker, Dianne Foster, Chuanhui Dong, Negar Asdaghi, Jose G Romano, Ralph L Sacco and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Observational
  2. Article
  3. Neighborhood socio-demographic profile associated with adequate transitions of stroke care: The transitions of care stroke disparities study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Racial and ethnic disparities in the usage and outcomes of ischemic stroke treatment in the United States.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Observational
  9. Article
  10. Disparities in transitions of acute stroke care: The transitions of care stroke disparities study methodological report.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sai P PolineniDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Enmanuel J PerezDepartment of Neurology Washington University in St. Louis MO.
Kefeng WangDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Carolina M GutierrezDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Jeffrey WalkerAmerican Heart Association Southeast Marietta GA.
Dianne FosterAmerican Heart Association Southeast Marietta GA.
Chuanhui DongDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Negar AsdaghiDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Jose G RomanoDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Ralph L SaccoDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Tatjana RundekDepartment of Neurology University of Miami Miller School of Medicine Miami FL.
Florida Stroke Registry
University of Miami · USAmerican Heart Association · USWashington University in St. Louis · US

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
STROKE INCIDENCE AND RISK FACTORS IN A TRI-ETHNIC REGIONR01NS029993 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ELKIND, MITCHELL S, SACCO, RALPH L. · 1993 to 2019
$19.2M
FAMILY STUDY OF STROKE RISK AND CAROTID ATHEROSCLEROSISR01NS040807 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BLANTON, SUSAN HALLORAN, RUNDEK, TATJANA · 2002 to 2022
$12.2M
The Data Management and BiostatisticsU54NS081763 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SACCO, RALPH L. · 2013 to 2017
$4.2M
Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
Disparities in Transition of Care after Acute Stroke Hospitalization: The Transition of Care Stroke Disparity Study (TCSD-S)R01MD012467 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROMANO, JOSE G, RUNDEK, TATJANA · 2017 to 2021
$3.6M
Mechanisms of Early Recurrence in Intracranial Atherosclerotic DiseaseR01NS084288 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIEBESKIND, DAVID SIGMUND, PRABHAKARAN, SHYAM · 2014 to 2018
$3.0M
Florida Regional Coordinating Center for the NINDS Stroke Trials NetworkU24NS107267 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JOSE G ROMANO · 2018 to 2026
$3.0M
Miami Clinical and Translational Science InstituteKL2TR000461 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SACCO, RALPH L. · 2012 to 2016
$2.1M
NCATS NIH HHS KL2 TR000461NCATS NIH HHS KL2 TR002737NCATS NIH HHS UL1 TR002736NIMHD NIH HHS R01 MD012467NINDS NIH HHS R01 NS029993NINDS NIH HHS R01 NS040807NINDS NIH HHS R01 NS084288NINDS NIH HHS U24 NS107267NINDS NIH HHS U54 NS081763
6 · The paper itself

Abstract

Background Less than 40% of acute stroke patients have computed tomography (CT) imaging performed within 25 minutes of hospital arrival. We aimed to examine the race-ethnic and sex differences in door-to-CT (DTCT) ≤25 minutes in the FSR (Florida Stroke Registry). Methods and Results Data were collected from 2010 to 2018 for 63 265 patients with acute ischemic stroke from the FSR and secondary analysis was performed on 15 877 patients with intravenous tissue plasminogen activator-treated ischemic stroke. Generalized estimating equation models were used to determine predictors of DTCT ≤25. DTCT ≤25 was achieved in 56% of cases of suspected acute stroke, improving from 36% in 2010 to 72% in 2018. Women (odds ratio [OR], 0.90; 95% CI, 0.87-0.93) and Black (OR, 0.88; CI, 0.84-0.94) patients who had strokes were less likely, and Hispanic patients more likely (OR, 1.07; CI, 1.01-1.14), to achieve DTCT ≤25. In a secondary analysis among intravenous tissue plasminogen activator-treated patients, 81% of patients achieved DTCT ≤25. In this subgroup, women were less likely to receive DTCT ≤25 (0.85, 0.77-0.94) whereas no significant differences were observed by race or ethnicity. Conclusions In the FSR, there was considerable improvement in acute stroke care metric DTCT ≤25 in 2018 in comparison to 2010. However, sex and race-ethnic disparities persist and require further efforts to improve performance and reduce these disparities.

Indexed as

Delayed DiagnosisHealthcare DisparitiesIschemic StrokeTime-to-TreatmentTomography, X-Ray ComputedAgedEthnicityFemaleFibrinolytic AgentsFloridaHospitalizationHumansMaleOutcome and Process Assessment, Health CareQuality ImprovementRegistriesFibrinolytic AgentsTissue Plasminogen Activatordisparitiesethnicityischemic strokeracesex

Identifiers

PMID33787282
PMCPMC8174374
OpenAlexW3144091603

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.