Evidence map›Paper›PMID 33787228›Full record

ArticleAnalytical chemistry2021

Detection and Quantification of Tightly Bound Zn

Shige Xing, Yao Lin, Liangyuan Cai, Prem N Basa, Austin K Shigemoto, Chengbin Zheng, Feng Zhang, Shawn C Burdette, Yi Lu

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Ratiometric Detection of ZnChemistry (Basel, Switzerland) · 2023
    Article
  2. Genetically encoded fluorescent sensors for metals in biology.Current opinion in chemical biology · 2023
    Review
  3. Recent progress in studies of photocages.Smart molecules : open access · 2023
    Review
  4. Simultaneous FeScience advances · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Shige XingDepartment of Chemistry, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Yao LinDepartment of Chemistry, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Liangyuan CaiDepartment of Chemistry, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Prem N BasaDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachusetts 01609-2280, United States.
Austin K ShigemotoDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachusetts 01609-2280, United States.
Chengbin ZhengKey Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, China.
Feng ZhangInstitute of Food Safety, Chinese Academy of Inspection & Quarantine, Beijing 100176, China.ORCID 0000-0002-7888-9669
Shawn C BurdetteDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachusetts 01609-2280, United States.ORCID 0000-0002-2176-0776
Yi LuDepartment of Chemistry, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-1221-6709
University of Illinois Urbana-Champaign · USWorcester Polytechnic Institute · USChinese Academy of Inspection and Quarantine · CNSichuan University · CN

Funding

Selection and Sensing Applications of DNAzymes Selective for Paramagnetic Metal IonsR01GM124316 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI LU, YI · 2017 to 2020
$1.4M
NIGMS NIH HHS R01 GM124316
6 · The paper itself

Abstract

DNAzymes have emerged as a powerful class of sensors for metal ions due to their high selectivity over a wide range of metal ions, allowing for on-site and real-time detection. Despite much progress made in this area, detecting and quantifying tightly bound metal ions, such as those in the blood serum, remain a challenge because the DNAzyme sensors reported so far can detect only mobile metal ions that are accessible to bind the DNAzymes. To overcome this major limitation, we report the use of a photocaged chelator, XDPAdeCage to extract the Zn

Indexed as

Biosensing TechniquesDNA, CatalyticChelating AgentsIonsSerumZincChelating AgentsDNA, CatalyticIonsZinc

Identifiers

PMID33787228
PMCPMC9169884
OpenAlexW3151278645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.