ArticleEMBO molecular medicine2021
Motile mosquito stage malaria parasites: ready for their close-up.
Article in EMBO molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 22 citations in OpenAlex.
- A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei.Parasites & vectors · 2023Article
- Mosquito bites and stage-specific antibody responses against Plasmodium falciparum in southern Ghana.Malaria journal · 2023Article
- Novel systems to study vector-pathogen interactions in malaria.Frontiers in cellular and infection microbiology · 2023Review
- Plasmodium sporozoite disintegration during skin passage limits malaria parasite transmission.EMBO reports · 2022Article
- Motile mosquito stage malaria parasites: ready for their close-up.EMBO molecular medicine · 2021Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many stages of the complex Plasmodium parasite life cycle, the eukaryotic pathogen that causes malaria, are extracellular and motile. This motility is essential for life cycle progression, and two studies in this issue of EMBO Molecular Medicine (Hopp et al, 2021; Ripp et al, 2021) examine the motility of two of these life cycle stages. These are the ookinete, which develops in the midgut of an infected mosquito vector, and the sporozoite, which is injected into the skin of an unsuspecting host by an infected mosquito, initiating the parasite life cycle in the human. Therapeutic targeting of the ookinete and sporozoite (Duffy & Patrick Gorres, 2020), which are profound bottlenecks in the life cycle, has recently received a great deal of attention in our battle to prevent the 400,000 deaths from malaria that occur every year (WHO, 2020).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.