Evidence map›Paper›PMID 33787056›Full record

ArticleEuropean journal of histochemistry : EJH2021

Comparison of CGRP distributions in the maxillary sinus and trigeminal ganglion between elderly dentulous and edentulous humans.

Hiroyuki Matsuda, Iwao Sato, Rieko Asaumi, Takuya Omotehara, Shinichi Kawata, Kenta Nagahori, Zhong-Lian Li, Masahiro Itoh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of histochemistry : EJH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hiroyuki MatsudaDepartment of Anatomy, Tokyo Medical University, Tokyo. hmatsuda@tokyo-med.ac.jp.
Iwao SatoDepartment of Anatomy, Tokyo Medical Univsersity. iwaoa1@tokyo-med.ac.jp.
Rieko AsaumiDepartment of Oral and Maxillofacial Radiology, School of Life Dentistry at Tokyo, The Nippon Dental University, Tokyo. asaumi-r@tky.ndu.ac.jp.
Takuya OmoteharaDepartment of Anatomy, Tokyo Medical University, Tokyo. omote@tokyo-med.ac.jp.
Shinichi KawataDepartment of Anatomy, Tokyo Medical University, Tokyo. shinichi@tokyo-med.ac.jp.
Kenta NagahoriDepartment of Anatomy, Tokyo Medical University, Tokyo. kenta-n@tokyo-med.ac.jp.
Zhong-Lian LiDepartment of Anatomy, Tokyo Medical University, Tokyo. zhonglan@tokyo-med.ac.jp.
Masahiro ItohDepartment of Anatomy, Tokyo Medical University, Tokyo. itomasa@tokyo-med.ac.jp.
Tokyo Medical University · JPNippon Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thickening of the Schneiderian membrane (SM, mucosa of the maxillary sinus) appears in the paranasal sinus. Information on SM thickening is available for patients receiving sinus lift treatments, which is a risk factor for SM excretory dysfunction. However, more information is needed on the structure of the SM and the relationship between the maxilla sinus and palatine with the alveolar bone and the SM for dental implant treatment in the human maxilla. One hundred twenty-six sides of the maxilla from 71 cadavers were subjected to cone-beam CT (CBCT) analysis and macroscopic and immunohistochemical observations in this study. A thickened SM was mainly observed in the middle region of the basal layer of the maxillary sinus (MS). Strong calcitonin gene-related peptide (CGRP)-positive reactions were observed in the alveolar bone, oral mucosa, mucosa of the maxillary sinus, and trigeminal ganglion (TG) cells in dentulous samples compared with edentulous samples. TG cells play important roles in delivering CGRP through axons to the mucosal gland and in regulating the maxilla-related thickening of the SM. These data could help determine CGRP functions in the mucosal gland and bone formation between dentulous and edentulous samples and indicate that CGRP may pass from the TG to the maxillary sinus glands.

Indexed as

AgedAged, 80 and overCalcitonin Gene-Related PeptideFemaleHumansImmunohistochemistryJaw, Edentulous, PartiallyMaleMaxillary SinusMiddle AgedNasal MucosaTrigeminal GanglionCalcitonin Gene-Related Peptide

Identifiers

PMID33787056
PMCPMC8054570
OpenAlexW3148233478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.