ArticleAnnals of surgical oncology2021
Relationship Between Early Postoperative Change in Total Psoas Muscle Area and Long-term Prognosis in Esophagectomy for Patients with Esophageal Cancer.
Article in Annals of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review and Meta-Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- Article
- Conduit size and the risk of delayed gastric conduit emptying after esophagectomy.Surgery today · 2026Article
- Clinical advantages of two vs. three courses of neoadjuvant chemotherapy using docetaxel + cisplatin + 5-fluorouracil to improve preoperative nutritional status and mitigate decreasing skeletal muscle in resectable esophageal cancer.International journal of clinical oncology · 2025Article
- Sarcopenia in Colorectal Cancer Surgery-Minimally Invasive vs. Open.Journal of cachexia, sarcopenia and muscle · 2025Article
- Current Status of Gastrectomy for Gastric Cancer in Oldest-old Patients Aged 85 Years or Older.Journal of gastrointestinal cancer · 2025Article
- Changes in Skeletal Muscle Mass in the First 3 Months Following Gastrointestinal Cancer Surgery: A Prospective Study.Annals of surgical oncology · 2024Article
- Percent vital capacity predicts postoperative sarcopenia after esophagectomy in initially nonsarcopenic esophageal cancer patients: a retrospective cohort study.Surgery today · 2024Article
- Low Daily Step Count Associated with Small Erector Spinae Muscle Area and Sarcopenia in Idiopathic Pulmonary Fibrosis.Internal medicine (Tokyo, Japan) · 2024Article
- Article
- ASO Author Reflections: The Impact of Early Skeletal Muscle Loss Within 1 Week After Esophagectomy on Long-term Prognosis in Patients with Esophageal Cancer.Annals of surgical oncology · 2021Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative sarcopenia following esophagectomy for esophageal cancer has become a severe problem due to the increasing number of elderly patients undergoing surgery. This study aimed to clarify the relationship between early postoperative skeletal muscle change and cancer prognosis, and propose effective interventions to prevent sarcopenia.
methodsThis study retrospectively analyzed 152 patients who underwent esophagectomy for esophageal cancer. Total psoas muscle area (TPA) was measured before surgery as baseline and on postoperative day 7 (± 2). The effect of early postoperative skeletal muscle loss on 5-year survival was investigated. Moreover, 5-year survival in patients with postoperative complications and a high inflammatory status, which were previously reported as poor prognostic factors of esophageal cancer, was also investigated.
resultsAmong the 152 patients, 52 (34.2%) showed a decrease in TPA, while 100 (65.8%) maintained their TPA. The TPA decreasing group exhibited poor 5-year overall survival (OS) (p = 0.003) and 5-year recurrence-free survival (RFS) (p < 0.001). The TPA decreasing group also showed a poor 5-year OS in patients who developed severe postoperative complications (p = 0.015). Multivariate analyses showed that decreased TPA was found to be independently associated with OS (p = 0.017) as well as RFS (p = 0.002).
conclusionsOur findings suggested a relationship between decreased TPA within 1 week after esophagectomy and long-term prognosis among patients with esophageal cancer. If TPA can be maintained, the prognosis was better even in cases with serious complications.
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