Evidence map›Paper›PMID 33786671›Full record

Trial reportLasers in medical science2021

Effect of cetrimide 2% with and without photodynamic therapy to reduce Streptococcus mutans burden in dentinal carious lesions.

Gabriele Giorgi Moro, Natalia Cunha Massat, Diana Roberta Pereira Grandizoli, Augusto Etchegaray Junior, Giovanna Rosa Degasperi, Carlos Eduardo Fontana, Sérgio Luiz Pinheiro

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gabriele Giorgi MoroDepartment of Restorative Dentistry, Pontifical Catholic University of Campinas (PUC Campinas), Campinas, SP, Brazil.ORCID https://orcid.org/0000-0001-5596-9589
Natalia Cunha MassatCenter for Life Sciences, Postgraduate Program in Health Sciences, PUC Campinas, Av. John Boyd Dunlop, s/n, Campinas, SP, 13034-685, Brazil.ORCID https://orcid.org/0000-0001-6835-4890
Diana Roberta Pereira GrandizoliCenter for Life Sciences, Postgraduate Program in Health Sciences, PUC Campinas, Av. John Boyd Dunlop, s/n, Campinas, SP, 13034-685, Brazil.ORCID https://orcid.org/0000-0001-9903-5681
Augusto Etchegaray JuniorCenter for Life Sciences, Postgraduate Program in Health Sciences, PUC Campinas, Av. John Boyd Dunlop, s/n, Campinas, SP, 13034-685, Brazil.ORCID https://orcid.org/0000-0002-0483-0373
Giovanna Rosa DegasperiCenter for Health Sciences, PUC-Campinas, Campinas, SP, Brazil.ORCID https://orcid.org/0000-0002-0317-2532
Carlos Eduardo FontanaCenter for Life Sciences, Postgraduate Program in Health Sciences, PUC Campinas, Av. John Boyd Dunlop, s/n, Campinas, SP, 13034-685, Brazil.ORCID https://orcid.org/0000-0002-2868-6839
Sérgio Luiz PinheiroCenter for Life Sciences, Postgraduate Program in Health Sciences, PUC Campinas, Av. John Boyd Dunlop, s/n, Campinas, SP, 13034-685, Brazil. slpinho@puc-campinas.edu.br.ORCID http://orcid.org/0000-0001-7157-4923
Pontifícia Universidade Católica de Campinas · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the use of cetrimide alone and combined with photodynamic therapy to reduce S. mutans burden in carious lesions. Sixty permanent third molars were sectioned and the coronal dentin exposed. A cariogenic challenge was performed using brain-heart infusion (BHI) medium supplemented and S. mutans ATCC 25175. Specimens were incubated in anaerobic jars at 37 °C for 15 days, with BHI renewed every 24 h. After 15 days, specimens were randomly divided into six groups (n = 10): C, control (no treatment); CHX, application of chlorhexidine 2%; CT, application of cetrimide 2%; CT+aPDT, application of cetrimide 2% followed by methylene blue dye and aPDT (antimicrobial photodynamic therapy: wavelength 660 nm, energy 4J, power 100 mW, spot size 0.0028 cm

Indexed as

Dental CariesPhotochemotherapyCetrimoniumHumansPhotosensitizing AgentsStreptococcus mutansCetrimoniumPhotosensitizing AgentsCavity disinfectionCetrimide (cetrimonium)Laser irradiationPhotodynamic therapyS. mutans

Identifiers

PMID33786671
PMCPMC8009689
OpenAlexW3144230746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.