ArticleThe journal of nutrition, health & aging2021
The Impact of Frailty on the Relationship between Life-Space Mobility and Quality of Life in Older Adults during the COVID-19 Pandemic.
Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- The devastating trio of sarcopenia, frailty, and COVID-19 - A systematic review and meta-analysis.Clinical nutrition ESPEN · 2022Pooled it
- Walking Aids and Locomotion Training in the Emergency Department: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Life Space in Community-Dwelling Older Adults: A Concept Analysis.Journal of advanced nursing · 2026Review
- Frailty and Social Isolation of Elderly Prostate Cancer Patients: A Chain Mediating and Network Analysis of Illness Perception and Acceptance.Nursing open · 2026Article
- An integrative review of loneliness and quality of life in older adults who lived alone during COVID-19: considerations for supporting reconnection.BMC geriatrics · 2025Review
- Influence of the SARS-CoV-2 pandemic and infection on musculoskeletal function.Scientific reports · 2025Observational
- Risk of sarcopenia and mobility of older adults during the COVID-19 pandemic: the longitudinal data from the REMOBILIZE study.Aging clinical and experimental research · 2024Article
- The influence of nationwide COVID-19 lockdown on the functional impairment and long-term survival of dependent people for carrying out basic activities of daily living in a neighborhood of the city of Madrid, Spain: Orcasitas Cohort Longitudinal Study.Frontiers in public health · 2024Article
- Resilient Adaptation Strategies: Unveiling Older Adults' Coping Dynamics Amidst the COVID-19 Pandemic.Journal of gerontological nursing · 2023Article
- A Comparison of Cognitive Performance, Depressive Symptoms, and Incidence of Falls in Brazilian Older Women with and without a Confirmed History of COVID-19.International journal of environmental research and public health · 2023Article
- The role of frailty on quality of life in older adults during the COVID-19 pandemic.Aging clinical and experimental research · 2023Article
- Quality of Physical Activity Participation Among Adults with Disabilities Through Pandemic Restriction.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2023Article
- Timed up-and-go performance is associated with objectively measured life space in patients 3 months after ischemic stroke: a cross-sectional observational study.Journal of neurology · 2023Observational
- Changes in respiratory, physical, and mental conditions in moderate and severe COVID-19 cases at our convalescent rehabilitation ward.Japanese journal of comprehensive rehabilitation science · 2023Article
- Impact of COVID-19 pandemic on mobility of older adults: A scoping review.International journal of older people nursing · 2023Article
- Hospital admission and the occurrence of delirium in older adults with physical frailty: cross-sectional study.Revista da Escola de Enfermagem da U S P · 2023Article
- Article
- Social distancing, emotional suffering, and cognitive performance in mature and older adults: a literature review.Dementia & neuropsychologia · 2023Review
- Life-Space Mobility and Objectively Measured Movement Behavior in Older Adults with Hypertension after Receiving COVID-19 Vaccination.International journal of environmental research and public health · 2022Article
- Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe COVID-19 pandemic has led to abrupt restrictions of life-space mobility. The impact of shelter-in-place orders on older adults' health and well-being is still unclear.
objectiveTo investigate the relationship between life-space mobility and quality of life (QoL) in older adults with and without frailty during the COVID-19 pandemic.
designMulticenter prospective cohort study based on structured telephone interviews.
settingFour geriatric outpatient clinics in the metropolitan area of Sao Paulo, Brazil.
participants557 community-dwelling adults aged 60 years and older. MEASUREMENTS: The Life-Space Assessment was used to measure community mobility before and during the COVID-19 pandemic, and a previously validated decrease of ≥ 5 points defined restricted life-space mobility. Frailty was assessed through the FRAIL (fatigue, resistance, ambulation, illnesses, and loss of weight) scale. The impact of shelter-in-place orders on QoL was evaluated with the question «How is the COVID-19 pandemic affecting your QoL?», to which participants could respond «not at all», «to some extent», or «to a great extent». We used ordinal logistic regressions to investigate the relationship between restricted life-space mobility and impact on QoL, adjusting our analyses for demographics, frailty, comorbidities, cognition, functionality, loneliness, depression, and anxiety. We explored whether frailty modified the association between life-space mobility and impact on QoL.
resultsParticipants were on average 80±8 years old, 65% were women, and 33% were frail. The COVID-19 quarantine led to a restriction of community mobility in 79% of participants and affected the QoL for 77% of participants. We found that restricted life-space mobility was associated with impact on QoL in older adults during the pandemic, although frailty modified the magnitude of the association (P-value for interaction=0.03). Frail participants who experienced restricted life-space mobility had twice the odds of reporting an impact on QoL when compared with non-frail individuals, with respective adjusted odds ratios of 4.20 (95% CI=2.36-7.50) and 2.18 (95% CI=1.33-3.58).
conclusionOlder adults experienced substantial decreases in life-space mobility during the COVID-19 pandemic, and this unexpected change impacted their QoL. Providers should be particularly watchful for the consequences of abrupt life-space restrictions on frail individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.