ArticleThe journal of nutrition, health & aging2021
Comparison of Three Frailty Scales for Prediction of Adverse Outcomes among Older Adults: A Prospective Cohort Study.
Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of Frailty Among Chinese Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.International journal of public health · 2023Pooled it
- Frailty Is a Risk Factor for Falls in the Older Adults: A Systematic Review and Meta-Analysis.The journal of nutrition, health & aging · 2023Pooled it
- Trial
- MedADL: high-throughput information extraction of functional status from electronic health records to advance frailty assessment in older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Metabolomic characterization of frailty identifies subtype-specific management strategies.NPJ digital medicine · 2025Article
- Concern About Falling Is a Predictor of Fall Risk in Older Patients With Cardiovascular Disease - A 1-Year Longitudinal Study.Circulation reports · 2025Article
- Metformin reduces the risk of frailty: evidence from a Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Genetic and phenotypic associations of frailty with cardiovascular indicators and behavioral characteristics.Journal of advanced research · 2025Article
- Screening for frailty and its association with activities of daily living, cognitive impairment, and falls among community-dwelling older adults in China.BMC geriatrics · 2024Article
- Association of frailty index with congestive heart failure, all-cause and cardiovascular mortality among individuals with type 2 diabetes: a study from National Health and Nutrition Examination Surveys (NHANES), 1999-2018.Diabetology & metabolic syndrome · 2023Article
- Association of sleep duration and physical frailty with cognitive function in older patients with coexisting atrial fibrillation and heart failure.Nursing open · 2023Article
- Comparison of three frailty screening instruments for prediction of adverse outcomes among older adults in the emergency department.Geriatrics & gerontology international · 2022Article
- Comparative Analysis of Three Frailty Assessment Tools: A Cross-Sectional Study.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the ability of Frailty Phenotype (FP), FRAIL and Frailty Index (FI) to predict adverse outcomes.
designA prospective cohort study.
settingA senior community in Beijing, China.
participantsA total of 188 older adults aged 65 years or older (mean age 84.0 ± 4.4 years, 58.5% female). MEASUREMENTS: Frailty was evaluated by FP, FRAIL and FI. The agreement between scales was assessed by Cohen kappa coefficient. The predictive value of the three scales for adverse outcomes during one-year follow-up period were analyzed using decision curve analysis(DCA) and receiver operating characteristic curve (ROC) analysis.
resultsFrailty ranged from 25% (FRAIL) to 42.6% (FI). The agreement between scales was moderate to good (Cohen's kappa coefficient 0.44~0.61). DCA showed though the curves of the scales overlapped across all relevant risk thresholds, clinical treating had a higher net benefit than "treat all" and "treat none" when risk of unplanned hospital visits ≥30%, risk of functional decline or falls ≥15%. The three scales had similar predictive value for unplanned hospital visits (area under ROC, AUC 0.63, 0.64 and 0.69). FRAIL and FI had similar predictive value for functional decline (AUC 0.63,0.65). FI had predictive value for falls (AUC 0.65).
conclusionsAll three scales showed clinical utility but FRAIL may be best in practice because it is simple. Multidimensional measures of frailty are better than unidimensional for prediction of adverse outcomes among older adults.
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