ArticleCritical care explorations2021
ABCDEF Bundle and Supportive ICU Practices for Patients With Coronavirus Disease 2019 Infection: An International Point Prevalence Study.
Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05049200 (Epidemiology of Weaning From Invasive Mechanical Ventilation in COVID-19. Observational and Multicenter Study.), which is not on this map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Epidemiology of Weaning From Invasive Mechanical Ventilation in COVID-19. Observational and Multicenter Study.
Who cites it
40 citing papers in PubMed.
- Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial.The Lancet. Respiratory medicine · 2023Trial
- Barriers and Facilitators to ICU Liberation Bundle Implementation and Compliance.Critical care explorations · 2026Article
- Article
- A rapid evaluation of quality of sedation and ventilation care processes for critically ill patients in Vietnam.PloS one · 2026Article
- Risk Factors of Post-Traumatic Stress Disorder Symptom Trajectories for ICU Bereaved Family Members.Annals of the American Thoracic Society · 2025Article
- Time series differences in coagulopathy in mechanically ventilated COVID-19 and bacterial pneumonia patients: a nationwide observational study in Japan.Thrombosis journal · 2025Article
- Early Rehabilitation Interventions by Physical Therapists for Severe COVID-19 Patients Were Associated With Decreased Incidence of Post-ICU Physical Impairment.Annals of rehabilitation medicine · 2025Article
- Impact of Nutritional Therapy during Intensive Care Unit Admission on Post-Intensive Care Syndrome in Patients with COVID-19.Annals of nutrition & metabolism · 2025Article
- From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome.Journal of intensive care · 2024Review
- Improving Outcomes in Mechanically Ventilated Adult ICU Patients Following Implementation of the ICU Liberation (ABCDEF) Bundle Across a Large Healthcare System.Critical care explorations · 2024Article
- Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study.Annals of intensive care · 2023Article
- Lessons Learned From a Systematic, Hospital-Wide Implementation of the ABCDEF Bundle: A Survey Evaluation.Critical care explorations · 2023Article
- Awakening and Breathing Coordination: A Mixed-Methods Analysis of Determinants of Implementation.Annals of the American Thoracic Society · 2023Article
- Perspectives on Sedation Among Interdisciplinary Team Members in ICU: A Survey Study.Critical care explorations · 2023Article
- Failure of First Transition to Pressure Support Ventilation After Spontaneous Awakening Trials in Hypoxemic Respiratory Failure: Influence of COVID-19.Critical care explorations · 2023Article
- Article
- Epidemiology of Weaning From Invasive Mechanical Ventilation in Subjects With COVID-19.Respiratory care · 2023Article
- Review
- Nutrition therapy in the intensive care unit during the COVID-19 pandemic: Findings from the ISIIC point prevalence study.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- Upcoming and urgent challenges in critical care research based on COVID-19 pandemic experience.Anaesthesia, critical care & pain medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate implementation of evidence-based and supportive cares in ICUs, such as the ABCDEF, nutrition therapy, and ICU diary, for patients with coronavirus disease 2019 infection in ICUs and their association with ICU clinical practice and setting.
designA worldwide, 2-day point prevalence study.
settingThe study was carried out on June 3, 2020, and July 1, 2020. A total of 212 ICUs in 38 countries participated. Clinicians in each participating ICU completed web-based online surveys. PATIENTS: The ICU patients with coronavirus disease 2019.
interventionsNone. MEASUREMENTS AND MAIN
resultsThe implementation rate for the elements of the ABCDEF bundle, other supportive ICU care measures, and implementation-associated structures were investigated. Data were collected for 262 patients, of whom 47.3% underwent mechanical ventilation and 4.6% were treated with extracorporeal membrane oxygenation. Each element was implemented for the following percentages of patients: elements A (regular pain assessment), 45%; B (both spontaneous awakening and breathing trials), 28%; C (regular sedation assessment), 52%; D (regular delirium assessment), 35%; E (early mobility and exercise), 47%; and F (family engagement and empowerment), 16%. The implementation of element E was 4% for patients on mechanical ventilation and 8% for patients on extracorporeal membrane oxygenation. Supportive care, such as protein provision throughout the ICU stay (under 1.2 g/kg for more than 50% of the patients) and introduction of ICU diary (25%), was infrequent. Implementation rates of elements A and D were higher in ICUs with specific protocols and fewer ICU beds exclusively for patients with coronavirus disease 2019 infection. Element E was implemented at a higher rate in ICUs that had more ICU beds assigned for them.
conclusionsThis point prevalence study showed low implementation of the ABCDEF bundle. Specific protocols and the number of ICU beds reserved for patients with coronavirus disease 2019 infection might be key factors for delivering appropriate supportive care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.