Evidence map›Paper›PMID 33786199›Full record

ReviewGlobal challenges (Hoboken, NJ)2021

Recent Advances on Nanomaterials to COVID-19 Management: A Systematic Review on Antiviral/Virucidal Agents and Mechanisms of SARS-CoV-2 Inhibition/Inactivation.

Anna Paula A Carvalho, Carlos A Conte-Junior

Open access · goldAbstract readReview
In one paragraph

Review in Global challenges (Hoboken, NJ), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Potential ofBioMed research international · 2022
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Facile synthesis of FeScientific reports · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. A Novel Antipathogenic Agent for Nonwoven Fabric.Biomedical materials & devices (New York, N.Y.) · 2022
    Article
  11. TiOACS biomaterials science & engineering · 2022
    Article
  12. Article
  13. Quantum dots against SARS-CoV-2: diagnostic and therapeutic potentials.Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) · 2022
    Review
  14. Review
  15. Article
  16. Metallic Structures: Effective Agents to Fight Pathogenic Microorganisms.International journal of molecular sciences · 2022
    Review
  17. A comprehensive review on efficient approaches for combating coronaviruses.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anna Paula A CarvalhoCOVID-19 Research Group Technological Development Support Laboratory (LADETEC) Department of Biochemistry Federal University of Rio de Janeiro (UFRJ) UFRJ Rio de Janeiro 21941-909 Brazil.ORCID https://orcid.org/0000-0001-9258-5947
Carlos A Conte-JuniorCOVID-19 Research Group Technological Development Support Laboratory (LADETEC) Department of Biochemistry Federal University of Rio de Janeiro (UFRJ) UFRJ Rio de Janeiro 21941-909 Brazil.ORCID https://orcid.org/0000-0001-6133-5080
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current pandemic of coronavirus disease 2019 (COVID-19) is recognized as a public health emergency of worldwide concern. Nanomaterials can be effectively used to detect, capture/inactivate or inhibit coronavirus cell entry/replication in the human host cell, preventing infection. Their potential for nanovaccines, immunoengineering, diagnosis, repurposing medication, and disinfectant surfaces targeting the novel coronavirus (SARS-CoV-2) is highlighted. In this systematic review the aim is to present an unbiased view of which and how nanomaterials can reduce the spread of COVID-19. Herein, the focus is on SARS-CoV-2, analyzing 46 articles retrieved before December 31, 2020. The interface between nanomaterials is described, and the main mechanisms to inhibit SARS-CoV-2 pathogenesis and viral inactivation are also discussed. Nanocarbons, biopolymeric, copper, and silver nanoparticles are potential antiviral and virucidal agents toward self-cleaning and reusable filter media and surfaces (e.g., facial masks), drug administration, vaccines, and immunodiagnostic assays. Trends in toxicology research and safety tests can help fill the main gaps in the literature and overcome health surveillance's challenges. Phytochemicals delivery by nanocarriers also stand out as candidates to target and bio-friendly therapy. Nanocellulose might fill in the gaps. Future research using nanomaterials targeting novel therapies/prophylaxis measures to COVID-19 and future outbreaks is discussed.

Indexed as

bioactive compoundscell mechanismsnanomedicinepolymeric nanoparticlesself‐cleaning surfaces

Identifiers

PMID33786199
PMCPMC7994982
OpenAlexW3133444323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.