Evidence map›Paper›PMID 33786121›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2021

Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?

Anna Pekařová, Matej Pekař, Marek Soltes, Lucia Havrlentová, Tereza Chovancová

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Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

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6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Anna PekařováDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Matej PekařDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Marek Soltes1 Department of Surgery, University of Pavol Jozef Safarik, Kosice, Slovak Republic.
Lucia HavrlentováDepartment of Surgery, Vitkovice Hospital, Ostrava, Czech Republic.
Tereza ChovancováDepartment of Surgery, Vitkovice Hospital, Ostrava, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified.

aimTo evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) - previously described sarcopaenia indicators - as possible risk factors for postoperative complications in patients after curative colon and rectal resections for colorectal cancer. MATERIAL AND

methodsConsecutive patients after elective curative colon or rectal resection for cancer at a single institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra.

resultsData of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences.

conclusionsPsoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preoperative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice.

Indexed as

colorectal cancercomplicationscomputed tomographypsoas densitysarcopaenia

Identifiers

PMID33786121
PMCPMC7991955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.