ArticleTherapeutic advances in musculoskeletal disease2021
Impact of sarcopenia on rehabilitation outcomes after total knee replacement in older adults with knee osteoarthritis.
Article in Therapeutic advances in musculoskeletal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06136039 (Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- High prevalence and multifactorial risks of sarcopenia in knee osteoarthritis: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Impact of sarcopenia on clinical outcomes of older adults undergoing total knee arthroplasty for osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Sarcopenia and Postoperative Outcomes Following Total Knee Arthroplasty: A Systematic Review of Observational Studies.Journal of clinical medicine · 2026Review
- Frailty and Sarcopenia as Predictors of Functional Recovery After Total Hip and Knee Arthroplasty: A Narrative Review.Journal of clinical medicine · 2026Review
- A prospective, single-center longitudinal study on the operational definition of sarcopenia in patients undergoing total knee arthroplasty.European geriatric medicine · 2026Article
- Association between the sarcopenia index and osteoarthritis: a cross-sectional and longitudinal study.European journal of medical research · 2026Article
- Low phase angle indicates poor muscle strength and physical performance in patients with knee osteoarthritis awaiting total knee arthroplasty.Scientific reports · 2025Article
- Chest CT-determined sarcopenia is associated with poorer functional outcomes in osteoarthritis patients undergoing total knee arthroplasty: a retrospective cohort study.Scientific reports · 2025Article
- Impact of Resistance Exercise and Nitrate Supplementation on Muscle Function and Clinical Outcomes After Knee Osteoarthritis Surgery in Middle-Aged Women with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.Journal of clinical medicine · 2025Article
- The Correlations of Sarcopenia and Obesity Status with Prevalence of Osteoarthritis in Older Adults.Geriatric orthopaedic surgery & rehabilitation · 2025Article
- Article
- Persistence of analgesic usage and opioid consumption in sarcopenic patients undergoing neuraxial anesthesia: a nationwide retrospective cohort study.Pain reports · 2024Article
- Article
- Comparative Analysis on the Effect of Sarcopenia in Patients with Knee Osteoarthritis before and after Total Knee Arthroplasty.Diseases (Basel, Switzerland) · 2023Article
- Observational
- Impact of Sarcopenia on Outcome of Exercise Therapy in Older Non-Hodgkin Lymphoma Patients.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionKnee osteoarthritis (KOA) is associated with an increased risk of sarcopenia, and aging-related muscle deterioration continues after total knee replacement (TKR). Low skeletal muscle mass index may influence postoperative rehabilitation outcomes. Through this study, we aimed to investigate the impact of preoperative sarcopenia on clinical outcomes after postoperative rehabilitation in older Asian adults.
methodsA total of 190 older adults (39 men, 151 women) were enrolled from two previous trials and were classified as having no sarcopenia, class I sarcopenia, or class II sarcopenia according to definitions provided by the Asian Working Group for Sarcopenia (AWGS) and the European Working Group on Sarcopenia in Older People (EWGSOP). All patients were retrospectively analyzed before (T
resultsAccording to the definitions of both the AWGS and EWGSOP, patients with class I and class II sarcopenia exhibited minor changes in TUGT, GS, TCR, and WOMAC-PF at T
conclusionsSarcopenia independently had negative impacts on the treatment effects of rehabilitation on physical mobility but not on pain outcome after TKR in older adults with KOA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.