Evidence map›Paper›PMID 33786052›Full record

ArticleIranian journal of parasitology

The in Vitro Antischistosomal Activity and Genotoxicity of the Active Ingredients of

Hadeer Abd El-Hak Rashed, Ali Hussein Abu Almaaty, Maha Farid Mohamed Soliman, Nahla Soliman El-Shenawy

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hadeer Abd El-Hak RashedZoology Department, Faculty of Science, Port Said University, Port Said, Egypt.
Ali Hussein Abu AlmaatyZoology Department, Faculty of Science, Port Said University, Port Said, Egypt.
Maha Farid Mohamed SolimanZoology Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
Nahla Soliman El-ShenawyZoology Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
Port Said University · EGSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, we assessed the in vitro antischistosomal activity of the active ingredients of

methodsThis study was conducted in Faculty of Science, Port said University, Egypt (2018). Adult worms were exposed to a range of concentrations of AL or CU, and worm survival was assessed 24 h post-exposure to calculate the lethal concentration of the compounds. Scanning electron microscopy was used to assess ultrastructural changes in the surface of AL- or CU- treated worms. The genotoxicities of AL and CU on

resultsWe determined the concentrations of AL and CU required to kill 50% of

conclusionBoth AL and CU exhibit antischistosomal activity; the study provided evidence suggesting that these compounds act through distinct mechanisms. These promising results encourage further investigation into these compounds as potential antischistosomal agents, either alone or as complementary treatments to praziquantel.

Indexed as

AllicinCurcuminDNASchistosoma mansoniUltrastructural

Identifiers

PMID33786052
PMCPMC7988669
OpenAlexW3129506359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.