Evidence map›Paper›PMID 33785625›Full record

ArticlemBio2021

Mycobacterium abscessus Strain Morphotype Determines Phage Susceptibility, the Repertoire of Therapeutically Useful Phages, and Phage Resistance.

Rebekah M Dedrick, Bailey E Smith, Rebecca A Garlena, Daniel A Russell, Haley G Aull, Vaishnavi Mahalingam, Ashley M Divens, Carlos A Guerrero-Bustamante, Kira M Zack, Lawrence Abad and 3 more

Abstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Leucine auxotrophic marker for genetic manipulation ofApplied and environmental microbiology · 2026
    Article
  3. Review
  4. Review
  5. Journal of bacteriology · 2026
    Review
  6. Smooth-to-rough morphotype switching, a mechanism of phage resistance inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Genome synthesis, assembly, and rebooting of therapeutically useful high G+C% mycobacteriophages.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. All the world's a phage.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. The role of colony morphotype in shaping gene essentiality inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. P3MA: A Promising Mycobacteriophage InfectingAntibiotics (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Genome sequence ofMicrobiology resource announcements · 2025
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Rebekah M DedrickDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Bailey E SmithDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Rebecca A GarlenaDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Daniel A RussellDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6894-2748
Haley G AullDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Vaishnavi MahalingamDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ashley M DivensDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Carlos A Guerrero-BustamanteDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Kira M ZackDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lawrence AbadDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Christian H GauthierDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Deborah Jacobs-SeraDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7838-3257
Graham F HatfullDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA gfh@pitt.edu.ORCID 0000-0002-6705-6821

Funding

Bacteriophage diversity, dynamics, function, and exploitationR35GM131729 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Graham F. Hatfull · 2019 to 2026
$3.6M
Rapid, efficient determination of bacteriophage susceptibilityR21AI151264 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HATFULL, GRAHAM F. · 2020 to 2021
$411k
Howard Hughes Medical Institute GT12053NIAID NIH HHS R21 AI151264NIGMS NIH HHS R35 GM131729
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Phage TherapyBacterial ProteinsCystic FibrosisHost-Pathogen InteractionsHost SpecificityHumansMutationMycobacteriophagesMycobacterium abscessusMycobacterium Infections, NontuberculousPhylogenyBacterial Proteinsbacteriophagesbacteriophage therapyMycobacterium abscessus

Identifiers

PMID33785625
PMCPMC8092298

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.