ArticlemBio2021
Shared Environment and Genetics Shape the Gut Microbiome after Infant Adoption.
Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Trial
- The Microbiota in the Diagnosis and Treatment of Autism Spectrum Disorder.International journal of molecular sciences · 2026Review
- Types and characteristics of shared microbiota within families of ethnic minorities in Inner Mongolia.Microbiology spectrum · 2026Article
- Off to a good start: current gaps and priorities in early-life microbiome research.FEMS microbiology reviews · 2026Review
- Shotgun metagenomic analysis reveals taxonomic and functional alterations in the gut microbiome across prodromal and symptomatic Lewy body disease.Frontiers in microbiomes · 2026Article
- Early life gut microbiome and its impact on childhood health and chronic conditions.Gut microbes · 2025Review
- Quantitative genetics of microbiome-mediated traits.Evolution; international journal of organic evolution · 2025Article
- Article
- Prioritizing precision: guidelines for the better use of population descriptors in human microbiome research.mSystems · 2025Review
- Pumping and hygiene practices are associated with bacterial load and microbial composition in human milk expressed at home.Journal of translational medicine · 2025Article
- A microbial symphony: a literature review of the factors that orchestrate the colonization dynamics of the human colonic microbiome during infancy and implications for future health.Microbiome research reports · 2025Review
- Birth and household exposures are associated with changes to skin bacterial communities during infancy.Evolution, medicine, and public health · 2025Article
- Estimates of microbiome heritability across hosts.Nature microbiology · 2024Review
- Environmental dispersal and host priority effect alternatively dominate intestinal microbiota succession of cultured shrimp along with host development.Marine life science & technology · 2024Article
- Social environment influences microbiota and potentially pathogenic bacterial communities on the skin of developing birds.Animal microbiome · 2024Article
- Social network dynamics, infant loss, and gut microbiota composition in female Colobus vellerosus during time periods with alpha male challenges.Primates; journal of primatology · 2024Article
- Review
- Tolerance to environmental pollution in the freshwater crustacean Asellus aquaticus: A role for the microbiome.Environmental microbiology reports · 2024Article
- Article
- Three species of axenic mosquito larvae recruit a shared core of bacteria in a common garden experiment.Applied and environmental microbiology · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The composition of the human gut microbiome is highly variable, and this variation has been repeatedly tied to variation in human health. However, the sources of microbial variation remain unclear, especially early in life. It is particularly important to understand sources of early life variation in the microbiome because the state of the microbiome in childhood can influence lifelong health. Here, we compared the gut microbiomes of children adopted in infancy to those of genetically unrelated children in the same household and genetically related children raised in other households. We observed that a shared home environment was the strongest predictor of overall microbiome similarity. Among those microbial taxa whose variation was significantly explained by our models, the abundance of a given taxon was more frequently explained by host genetic similarity (relatedness), while the presence of a given taxon was more dependent upon a shared home environment. This suggests that although the home environment may act as a species source pool for the gut microbiome in childhood, host genetic factors likely drive variation in microbial abundance once a species colonizes the gut.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.