ArticlemBio2021
Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 40 citations in OpenAlex.
- Optimized Surveillance Testing for ToxigenicmedRxiv : the preprint server for health sciences · 2026Article
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- Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity.Mucosal immunology · 2025Article
- Unravelling three-way interactions betweenJournal of medical microbiology · 2025Review
- The interplay between host immunity andmBio · 2025Review
- Article
- Serotype 2 Streptococcus suis growth inhibition mediated by intraspecies contact-dependent mechanism.Scientific reports · 2025Article
- Unique growth and morphology properties of Clade 5bioRxiv : the preprint server for biology · 2025Article
- Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy.PLoS pathogens · 2025Article
- Review
- Protection against Clostridioides difficile disease by a naturally avirulent strain.Cell host & microbe · 2025Article
- Harnessing the human gut microbiota: an emerging frontier in combatting multidrug-resistant bacteria.Frontiers in immunology · 2025Review
- Article
- Bacillus subtilis Intraspecies Interactions Shape Probiotic Activity Against Salmonella Typhimurium.Microbial biotechnology · 2024Article
- Protection againstbioRxiv : the preprint server for biology · 2024Article
- The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia.PLoS pathogens · 2024Article
- Article
- Microbiota-mediated colonization resistance: mechanisms and regulation.Nature reviews. Microbiology · 2023Review
- Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation.NPJ biofilms and microbiomes · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Jhansi L LeslieDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-5600-210X
Matthew L JeniorDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0003-1884-3543
Kimberly C VendrovDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-9131-5272
Alexandra K StandkeDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-7600-6124
Madeline R BarronDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-9077-2714
Tricia J O'BrienDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Lavinia UnverdorbenDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Pariyamon ThaprawatDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-8058-1743
Ingrid L BerginThe Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Patrick D SchlossDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-6935-4275
Vincent B YoungDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA youngvi@umich.edu.ORCID 0000-0003-3687-2364
University of Michigan · US
Funding
MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3MUniversity of Michigan Center for Gastrointestinal ResearchP30DK034933 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OWYANG, CHUNG · 1986 to 2021
$22.5MPilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3MSystems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8MMolecular Mechanisms of Microbial Pathogenesis Training ProgramT32AI007528 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 1998 to 2024
$6.8MMichigan Mouse Metabolic Phenotyping CenterU2CDK110768 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELIAS, CAROL FUZETI · 2016 to 2021
$6.2MThe role of the Western diet in increasing severity of Clostridium difficile infectionF32DK124048 · NIDDK · UNIVERSITY OF VIRGINIA · PI LESLIE, JHANSI LAKSHMI MARGARET · 2020 to 2022
$138kNIAID NIH HHS T32 AI007528NIAID NIH HHS U01 AI124255NIDDK NIH HHS F32 DK124048NIDDK NIH HHS P30 DK034933NIDDK NIH HHS P30 DK089503NIDDK NIH HHS U2C DK110768NIGMS NIH HHS T32 GM007863
Abstract
PubMed holds no abstract for this paper.
Indexed as
AntibiosisBiological TherapyAnimalsClostridioides difficileClostridium InfectionsFemaleGlycineHumansMaleMiceMice, Inbred C57BLMicrobiotaSpores, BacterialVirulenceGlycineamino acidsClostridioides difficilecompetitiongerminationmurine model
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.