ArticleClinical lymphoma, myeloma & leukemia2021
The Impact of Socioeconomic Risk Factors on the Survival Outcomes of Patients With Newly Diagnosed Multiple Myeloma: A Cross-analysis of a Population-based Registry and a Tertiary Care Center.
Article in Clinical lymphoma, myeloma & leukemia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Disparities in survival of hematologic malignancies in the context of social determinants of health: a systematic review.Blood advances · 2023Pooled it
- Examination of insurance type and cancer treatments with administrative burdens and financial toxicity in a sample of cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Social disruption after cancer: longitudinal changes in marital status, residence, and income among over 450,000 cancer patients.Cancer causes & control : CCC · 2026Article
- Observational
- Cumulative deficits frailty index and relationship status predict survival in multiple myeloma.Blood advances · 2025Article
- Income and education affect prognosis and treatment in symptomatic myeloma : A population-based study on 8672 multiple myeloma patients diagnosed 2008-2021 from the Swedish myeloma registry.Annals of hematology · 2025Article
- Development of Item Banks to Assess Financial Hardship in Cancer Survivors Using Item Response Theory.Frontiers in cancer control and society · 2025Article
- Addressing financial hardship in malignant hematology and hematopoietic cell transplant: a team approach.Blood advances · 2024Article
- Financial hardship after cancer: revision of a conceptual model and development of patient-reported outcome measures.Future science OA · 2024Article
- Global disparities in patients with multiple myeloma: a rapid evidence assessment.Blood cancer journal · 2023Article
- Hospital facility characteristics and socioeconomic factors on outcomes and treatment in patients with multiple myeloma: National Cancer Database analysis.Annals of hematology · 2023Article
- Health Disparities Experienced by Hispanic Americans with Multiple Myeloma: A Systematic Review.Clinical hematology international · 2023Article
- Article
- Socioeconomic status-based survival disparities and nomogram prediction for patients with multiple myeloma: Results from American and Chinese populations.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
25 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMultiple myeloma (MM) is a heterogeneous clonal plasma cell disorder leading to differences in clinical outcomes such as overall survival (OS) among patients. We hypothesized that with expensive, novel therapeutic agents and paradigm shifts to maintain continuous therapy and improvement in OS, patients with MM are subject to the pressures of financial toxicity and the need for social support, which may be of prognostic importance. MATERIALS AND
methodsIn this study, we examined the records of 122,458 patients from the National Cancer Database (NCDB) to determine the significance of socioeconomic factors such as estimated annual household income and education level, which were based on the patient's ZIP Code and the United States Census Bureau's 5-year report from 2008 to 2012. These socioeconomic factors, in addition to marital status, were then assessed individually and as a cumulative socioeconomic score for prognostic significance in a cohort of 2543 patients treated at a tertiary care center utilizing known biologic risk factors, such as cytogenetic risk, International Staging System classification, and serum lactate dehydrogenase levels.
resultsOnly marital status and estimated annual household income at diagnosis negatively impacted OS in a univariate analysis, but not in the context of a multivariable analysis incorporating known biologic risk factors.
conclusionFuture analyses in other academic and non-academic centers located in urban and rural regions are required to understand the socioeconomic drivers of OS disparity among patients with MM observed nationally.
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