Evidence map›Paper›PMID 33785077›Full record

Trial reportAlzheimer's research & therapy2021

The efficacy of exergaming in people with major neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial.

Nathalie Swinnen, Mathieu Vandenbulcke, Eling D de Bruin, Riekje Akkerman, Brendon Stubbs, Joseph Firth, Davy Vancampfort

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Alzheimer's research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04436302 (The Efficacy of Exergaming in People With Major Neurocognitive Disorder Residing in Long-term Care Facilities), which is not on this map. Cited by 41 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 14 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04436302 naunknown statusnot on this map

The Efficacy of Exergaming in People With Major Neurocognitive Disorder Residing in Long-term Care Facilities: A Randomized Controlled Trial

TypeinterventionalSponsorDavy VancampfortRan2019 to 2020Enrolled50ConditionsRandomised Controlled Trial, Major Neurocognitive Disorder, Long-term Care Facility, Physical ActivityArmsExergame device
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 14 syntheses or guidelines pooled it, 86 citations in OpenAlex.

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  9. Exergaming for dementia and mild cognitive impairment.The Cochrane database of systematic reviews · 2024
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  16. "Brain-IT": Exergame training with biofeedback breathing in neurocognitive disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Nathalie SwinnenKU Leuven Department of Rehabilitation Sciences, Leuven, Belgium.
Mathieu VandenbulckeUniversity Psychiatric Centre KU Leuven, Leuven, Kortenberg, Belgium.
Eling D de BruinDepartment of Health Sciences and Technology, Institute of Human Movement Sciences and Sport, ETH Zürich, Leopold-Ruzicka-Weg 4, 8093, Zürich, Switzerland. eling.debruin@hest.ethz.ch.
Riekje AkkermanLong-term care facility De Wingerd, Leuven, Belgium.
Brendon StubbsSouth London and Maudsley NHS Foundation Trust, Denmark Hill, London, UK.
Joseph FirthDivision of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Davy VancampfortKU Leuven Department of Rehabilitation Sciences, Leuven, Belgium.
KU Leuven · BEETH Zurich · CHSouth London and Maudsley NHS Foundation Trust · GBWestern Sydney University · AU

Funding

Medical Research Council MR/T021780/1
6 · The paper itself

Abstract

backgroundIt is currently unknown whether exergaming is efficacious in people with major neurocognitive disorder (MNCD) residing in long-term care facilities. This pilot randomized controlled trial (RCT) explored the efficacy of a stepping exergame program on gait speed, balance, mobility, reaction time, cognitive and neuropsychiatric outcomes, quality of life, and daily life functioning in people with MNCD residing in long-term care facilities.

methodsParticipants were randomly assigned to 8 weeks, three times weekly, 15 min of exergaming versus watching preferred music videos. The exergame device consisted of a pressure-sensitive step training platform on which participants performed stepping movements to play the games. The device automatically adapted the training level to the participants' capabilities. The Short Physical Performance Battery (SPPB), step reaction time test (SRTT), Montréal Cognitive Assessment (MoCA), Neuropsychiatric Inventory (NPI), Cornell Scale for Depression in Dementia (CSDD), Dementia Quality of Life (DQoL), and Katz Activities of Daily Living (Katz ADL) were assessed at baseline and post-intervention. A Quade's non-parametric ANCOVA controlling for baseline values with post hoc Bonferroni correction (p < 0.00625) was used to analyze pre- and post-differences between the groups. Partial eta-squared (η

resultsForty-five of 55 randomized inpatients with mild to moderate MNCD (Mini-Mental State Examination score = 17.2 ± 4.5; aged 70-91; 35 women) completed the study. The exergame group (n = 23) demonstrated improvements in gait speed (p < 0.001, η

conclusionsThe findings of this pilot RCT suggest that an individually adapted exergame training improves lower extremity functioning, cognitive functioning and step reaction time and symptoms of depression in inpatients with MNCD residing in long-term care facilities.

trial registrationClinicalTrials.gov, NCT04436302.

Indexed as

DementiaVideo GamesFemaleHumansLong-Term CareNeurocognitive DisordersPilot ProjectsBrain plasticityCognitionDementiaDepressionPhysical activityPhysical fitnessSerious exergames

Identifiers

PMID33785077
PMCPMC8008333
OpenAlexW3142417005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.