Evidence map›Paper›PMID 33784835›Full record

SynthesisClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Antiphospholipid Antibodies in Sickle Cell Disease: A Systematic Review and Exploratory Meta-Analysis.

Mira Merashli, Alessia Arcaro, Maria Graf, Matilde Caruso, Paul R J Ames, Fabrizio Gentile

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Mira MerashliDepartment of Internal Medicine, Division of Rheumatology, 11238American University of Beirut, Beirut, Lebanon.
Alessia ArcaroDepartment of Medicine & Health Sciences, 11238University of Molise, Campobasso, Italy.
Maria GrafImmunohaematology and Transfusion Medicine Unit, 165474Federico II University Hospital, Naples, Italy.ORCID https://orcid.org/0000-0002-5511-8036
Matilde CarusoTransfusion Medicine Unit, 18523Cardarelli Hospital, Campobasso, Italy.
Paul R J AmesImmune Response & Vascular Disease Unit, 50106Nova University, Lisbon, Portugal.
Fabrizio GentileDepartment of Medicine & Health Sciences, 11238University of Molise, Campobasso, Italy.ORCID https://orcid.org/0000-0002-6704-3115
University of Molise · ITAmerican University of Beirut · LBDumfries and Galloway Royal Infirmary · GBFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically addressed. Our aim was to evaluate potential links between SCD and aPL in all age groups. EMBASE/PubMed was screened from inception to May 2020 and Peto odds ratios for rare events were calculated. The pooled prevalence (PP) of IgG anticardiolipin antibodies (aCL) was higher in individuals with SCD than in controls (27.9% vs 8.7%,

Indexed as

Anemia, Sickle CellAntibodies, AntiphospholipidFemaleHumansMaleAntibodies, Antiphospholipidanticardiolipin antibodiesantiphospholipid antibodiesleg ulcerslupus anticoagulantmeta-analysissickle cell disease

Identifiers

PMID33784835
PMCPMC8020102
OpenAlexW3141899524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.