Evidence map›Paper›PMID 33784696›Full record

ArticleRespiration; international review of thoracic diseases2021

Pulmonary Rehabilitation in Patients Recovering from COVID-19.

Elisabetta Zampogna, Mara Paneroni, Stefano Belli, Maria Aliani, Alessandra Gandolfo, Dina Visca, Maria Teresa Bellanti, Nicolino Ambrosino, Michele Vitacca

Registry-linked trialAbstract read
In one paragraph

Article in Respiration; international review of thoracic diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05813873 (The Use of Incentive Spirometry), which is not on this map. Cited by 63 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05813873 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

The Use of Incentive Spirometry (Triflow) in Patients With Long Covid

TypeinterventionalSponsorEuropean University CyprusRan2022 to 2026Enrolled70ConditionsLong COVIDArmsTriflow, Control
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  2. Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review.International journal of environmental research and public health · 2023
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Elisabetta ZampognaRespiratory Rehabilitation of the Institute of Tradate, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, Italy.
Mara PaneroniRespiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici Scientifici Maugeri, IRCCS, Brescia, Italy.
Stefano BelliRespiratory Rehabilitation of the Institute of Veruno, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, Italy.
Maria AlianiRespiratory Rehabilitation of the Institute of Bari, Istituti Clinici Scientifici Maugeri, IRCCS, Bari, Italy.
Alessandra GandolfoRespiratory Rehabilitation of the Institute of Pavia, Istituti Clinici Scientifici Maugeri, IRCCS, Pavia, Italy.
Dina ViscaRespiratory Rehabilitation of the Institute of Tradate, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, Italy.
Maria Teresa BellantiRespiratory Rehabilitation of the Institute of Veruno, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, Italy.
Nicolino AmbrosinoRespiratory Rehabilitation of the Institute of Montescano, Istituti Clinici Scientifici Maugeri, IRCCS, Montescano, Italy.
Michele VitaccaRespiratory Rehabilitation of the Institute of Lumezzane, Istituti Clinici Scientifici Maugeri, IRCCS, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn hospitalized patients recovering from the SARS-coronavirus-2 disease 19 (COVID-19), high prevalence of muscle weakness and physical performance impairment has been observed.

objectivesThe aim of this study was to evaluate the effectiveness of pulmonary rehabilitation in these subjects in a real-life setting.

methodsRetrospective data analysis of patients recovering from COVID-19, including those requiring assisted ventilation or oxygen therapy, consecutively admitted to an in-patient pulmonary rehabilitation program between April 1 and August 15, 2020. Short Physical Performance Battery (SPPB: primary outcome), Barthel Index (BI), and six-min walking distance were assessed as outcome measures.

resultsData of 140 patients were analyzed. After rehabilitation, patients showed improvements in SPPB {from: (median [IQR]) 0.5 (0-7) to 7 (4-10), p < 0.001} and BI (from 55 [30-90] to 95 [65-100], p < 0.001), as well as in other assessed outcome measures. The proportion of patients unable at admission to stand, rise from a chair and walk was significantly reduced (p < 0.00).

conclusionsPulmonary rehabilitation is possible and effective in patients recovering from COVID-19. Our findings may be useful to guide clinicians taking care of patients surviving COVID-19 infection.

Indexed as

Respiratory TherapyAgedCOVID-19DyspneaExercise TestExercise TherapyFemaleHumansLength of StayMaleMiddle AgedPersons with DisabilitiesRetrospective StudiesDyspnoeaExercise capacityExercise trainingPulmonary rehabilitation

Identifiers

PMID33784696
PMCPMC8089404

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.