Evidence map›Paper›PMID 33784492›Full record

ArticlePharmaceutical biology2021

Effect of

Andrea Catalina Zepeda-Peña, Carmen Magdalena Gurrola-Díaz, José Alfredo Domínguez-Rosales, Pedro Macedonio García-López, Juan Carlos Pizano-Andrade, Zamira Helena Hernández-Nazará, Belinda Vargas-Guerrero

Abstract readComparative Study
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Nutrients · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea Catalina Zepeda-PeñaInstituto de Investigación en Enfermedades Crónico Degenerativas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0003-1714-0213
Carmen Magdalena Gurrola-DíazInstituto de Investigación en Enfermedades Crónico Degenerativas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0002-9851-8961
José Alfredo Domínguez-RosalesInstituto de Investigación en Enfermedades Crónico Degenerativas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0002-8560-5855
Pedro Macedonio García-LópezDepartamento de Botánica y Zoología, Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Zapopan, México.ORCID https://orcid.org/0000-0001-9551-6875
Juan Carlos Pizano-AndradeDepartamento de Botánica y Zoología, Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Zapopan, México.ORCID https://orcid.org/0000-0003-2784-322X
Zamira Helena Hernández-NazaráInstituto de Investigación en Enfermedades Crónico Degenerativas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0003-2319-8470
Belinda Vargas-GuerreroInstituto de Investigación en Enfermedades Crónico Degenerativas, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México.ORCID https://orcid.org/0000-0002-9112-5153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextGamma conglutin (Cγ) from lupine species represents a potential complementary treatment for type 2 diabetes mellitus (T2DM) because of its hypoglycaemic effect. However, its underlying mechanism of action is not fully known.

objectiveTo evaluate whether Cγ from MATERIALS AND

methodsGamma conglutin isolated from

resultsOral treatment with either Cγ or metformin reduced serum glucose level to 86.30 and 74.80 mg/dL, respectively ( DISCUSSION AND

conclusionsTreatment with Cγ from

Indexed as

AnimalsBlood GlucoseDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Gene Expression Regulation, EnzymologicHypoglycemic AgentsLupinusMaleMetforminMitogen-Activated Protein Kinase 8Plant ProteinsRatsRats, WistarStreptozocinBlood GlucoseHypoglycemic AgentsMetforminMitogen-Activated Protein Kinase 8Plant ProteinsStreptozocinHypoglycaemic effectinsulin resistancelegumelupinevegetal protein

Identifiers

PMID33784492
PMCPMC8018548

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.