ArticleAmerican journal of respiratory and critical care medicine2021
Ventilatory Variables and Mechanical Power in Patients with Acute Respiratory Distress Syndrome.
2 registry-linked trialsOpen access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 195 papers, 6 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
195citing papers in PubMed, 6 pooled it
45.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Specific Mechanical Power Assessment in Patients With Acute Respiratory Distress Syndrome
Effect of Inhalational Sedation on Mechanical Power in Mechanically Ventilated Patients: a Pilot Open-label Randomized Controlled Study
Who cites it
195 citing papers in PubMed, 6 syntheses or guidelines pooled it, 424 citations in OpenAlex.
- The Association Between Mechanical Power and Mortality in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Systematic Review and Meta-Analysis.Critical care medicine · 2026Pooled it
- Effect of driving pressure-limiting strategies on outcomes of patients with ARDS: a meta-analysis of randomized controlled trials.Critical care (London, England) · 2026Pooled it
- Physiological effects of noninvasive respiratory support strategies in adults with acute hypoxemic respiratory failure: a systematic review and network meta-analysis.Critical care (London, England) · 2025Pooled it
- Is EIT-guided positive end-expiratory pressure titration for optimizing PEEP in ARDS the white elephant in the room? A systematic review with meta-analysis and trial sequential analysis.Journal of clinical monitoring and computing · 2024Pooled it
- AARC Clinical Practice Guideline: Patient-Ventilator Assessment.Respiratory care · 2024Guideline
- Electrical impedance tomography-guided positive end-expiratory pressure titration in ARDS: a systematic review and meta-analysis.Intensive care medicine · 2024Pooled it
- Mechanical Power and the Association with Postoperative Impaired Oxygenation and Pulmonary Complications in Orthopedic Patients: Post Hoc Analysis of a Cluster Factorial Randomized Trial.Anesthesiology · 2026Trial
- Mechanical power guided lung protective ventilation in acute respiratory failure using the VentCoach approach.Scientific reports · 2026Trial
- Protective mechanical ventilation controlled by the real-time mechanical power measurement.Journal of clinical monitoring and computing · 2026Trial
- Trial
- Adjustment of positive end-expiratory pressure based on body mass index during general anaesthesia: a randomised controlled trial.Anaesthesia · 2025Trial
- The effect of bilateral rectus sheath and oblique subcostal transversus abdominis plane blocks on mechanical power in patients undergoing laparoscopic cholecystectomy surgery: a randomized controlled trial.BMC anesthesiology · 2025Trial
- Effect of automated versus conventional ventilation on mechanical power of ventilation-A randomized crossover clinical trial.PloS one · 2024Trial
- Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial.Critical care (London, England) · 2023Trial
- Esophageal pressure monitoring and ECCO 2 R: a personalized approach to ultraprotective mechanical ventilation in ARDS patients.Medical gas research · 2026Article
- Respiratory mechanics modifies the impact of ventilator settings on clinical outcome in patients with acute brain injury.Intensive care medicine · 2026Article
- Volatile anesthetic sedation in acute respiratory distress syndrome.Intensive care medicine · 2026Review
- Effects of PERMISSive lung-protective ventilation on outcome in critically ill, invasively ventilated patients (PERMISS): protocol for a feasibility and safety randomised clinical trial.BMJ open respiratory research · 2026Article
- Ventilatory Parameters and Adjunctive Therapies Associated with ICU Mortality in Severe Pneumonia: A Large Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.Intensive care medicine · 2026Review
135 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 4 countries.
Eduardo L V CostaLaboratório de Pneumologia, Laboratório de Investigação Médica 09, Disciplina de Pneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.ORCID 0000-0002-6941-3626
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Laurent J BrochardInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
Roy BrowerDivision of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Ary Serpa-NetoHospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.
Alexandre B CavalcantiInstituto de Pesquisas Hospital do Coração-Hospital do Coração, São Paulo, São Paulo, Brazil.
Alain MercatDépartement de Médecine Intensive-Réanimation, Centre Hospitalier Universitaire d'Angers, Université d'Angers, Angers, France.
Maureen MeadeDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Caio C A MoraisLaboratório de Pneumologia, Laboratório de Investigação Médica 09, Disciplina de Pneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Ewan GoligherInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-0990-6701
Carlos R R CarvalhoLaboratório de Pneumologia, Laboratório de Investigação Médica 09, Disciplina de Pneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Marcelo B P AmatoLaboratório de Pneumologia, Laboratório de Investigação Médica 09, Disciplina de Pneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRSt. Michael's Hospital · CACentre Hospitalier Universitaire d'Angers · FRHospital do Coração · BRHospital Israelita Albert Einstein · BRJohns Hopkins University · USMcMaster University · CAUniversity Health Network · CA
Funding
CIHR
Abstract
PubMed holds no abstract for this paper.
Indexed as
MortalityAdultAgedEnergy TransferFemaleHumansMaleMiddle AgedPressureRespiration, ArtificialRespiratory Distress SyndromeRespiratory RateVentilator-Induced Lung Injuryadultartificialrespirationrespiratory distress syndromeventilator-induced lung injury
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT05410262ClinicalTrials.gov
NCT05559970ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.