ArticlePloS one2021
Combustible cigarettes, heated tobacco products, combined product use, and periodontal disease: A cross-sectional JASTIS study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06480877 (Effect of Aerosol From Tobacco Heating System and Tobacco Cigarette Smoke on Periodontal Tissues and Its Specific Microbiome), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Aerosol From Tobacco Heating System and Tobacco Cigarette Smoke on Periodontal Tissues and Its Specific Microbiome
Who cites it
10 citing papers in PubMed.
- Heated tobacco product-derived aerosol extract impairs gingival epithelial barrier function via CXADR downregulation.Toxicology reports · 2026Article
- The role of smoking habits in periodontal health and disease: A cross-sectional study.Tobacco induced diseases · 2026Article
- Switching from cigarette use to dual use with heated tobacco products and severe periodontitis risk.Frontiers in oral health · 2026Article
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- Article
- Association between use of heated tobacco products and long-term respiratory effects considering smoking history: internet-based cross-sectional study in Japan.BMC public health · 2024Article
- Evaluating the Effects of Cigarette Smoking and Heated Tobacco Products on Hard Dental Tissues: A Comparative Histological and Colorimetric Analysis.Clinical and experimental dental research · 2024Article
- Periodontal Health Status in Adults Exposed to Tobacco Heating System Aerosol and Cigarette Smoke vs. Non-Smokers: A Cross-Sectional Study.Dentistry journal · 2024Article
- Perceived relative harm of heated tobacco products and electronic cigarettes and its association with use in smoke-free places: A cross-sectional analysis of Korean adults.Tobacco induced diseases · 2022Article
- [Association of cigarette consumption, nicotine derivatives and cannabis with periodontal disease. A review].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCombustible cigarettes have detrimental effects on periodontal disease. However, little evidence is available regarding new heated tobacco product (HTP) use and combined product use (both combustible cigarettes and HTPs). This study aimed to examine the association of combustible cigarettes, HTPs, and combined product use with periodontal disease simultaneously. MATERIALS AND
methodsThis cross-sectional study was conducted using data from the 2019 arm of the longitudinal Japan "Society and New Tobacco" Internet Survey. Combustible cigarette users, HTP users, combined product users, never-users, and former users' data were separately obtained. In the present study, the primary outcome was self-reported periodontal disease. We estimated adjusted prevalence ratios (PRs) and confidence intervals (CIs) using multivariable modified Poisson regression analysis after adjusting for 12 confounders.
resultsOf the 10,439 JASTIS respondents, the numbers of users of combustible cigarettes only, HTPs only, and both products were 1,304, 437, and 1,049, respectively. Compared with never-users, HTP use was significantly associated with the prevalence of self-reported periodontal diseases (PR 1.43, 95% CI 1.03-1.62). Moreover, former users, combustible cigarette users, and combined product users also showed significant associations (PR 1.56, 95% CI 1.35-1.80; PR 1.29, 95% CI 1.03-1.62; and PR 1.55, 95% CI 1.20-1.99, respectively).
conclusionsUsers of HTPs, combustible cigarettes, and combined products as well as former users were all significantly associated with a higher prevalence of periodontal diseases compared to never-users.
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