Evidence map›Paper›PMID 33783953›Full record

ArticleJournal of thrombosis and haemostasis : JTH2021

A case report of acquired hemophilia following COVID-19 vaccine.

Mansoor Radwi, Sara Farsi

Abstract readCase Reports
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mansoor RadwiDepartment of Hematology, College of Medicine, University of Jeddah, Jeddah, Saudi Arabia.ORCID 0000-0003-4402-4496
Sara FarsiDepartment of Anesthesia and Critical Care, King AbdulAziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0001-7694-4057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquires hemophilia A (AHA) is rare bleeding condition commonly associated with malignancy, autoimmune disease, or pregnancy. We report a case of a 69-year-old gentleman who developed bleeding symptoms after receiving COVID-19 vaccine. Laboratory testing showed isolated prolongation of the activated partial thromboplastin time, and normal von Willebrand factor. Further testing confirmed the presence of factor VIII inhibitor. To date, no cases of AHA have been reported after exposure to COVID-19 vaccine. There have been two cases of AHA following seasonal flu and H1N1 vaccination, as well as two cases of AHA following COVID-19 infection. We present a summary of these cases and review of literature of autoimmune reactions following vaccination.

Indexed as

COVID-19Hemophilia AInfluenza A Virus, H1N1 SubtypeAgedCOVID-19 VaccinesFactor VIIIFemaleHumansMalePregnancySARS-CoV-2COVID-19 VaccinesFactor VIIIglucocorticoidshemophilia Ahemorrhageimmune systemimmunosuppression

Identifiers

PMID33783953
PMCPMC8250362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.