Evidence map›Paper›PMID 33783917›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2021

Should beta-blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome?

Mari Amino, Tomokazu Fukushima, Atsushi Uehata, Chiemi Nishikawa, Seiji Morita, Yoshihide Nakagawa, Tsutomu Murakami, Koichiro Yoshioka, Yuji Ikari

Abstract readCase Reports
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Kounis Syndrome: Review of Clinical Cases.Cardiovascular & hematological disorders drug targets · 2024
    Review
  5. Article
  6. Should beta-blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome?Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mari AminoDepartment of Cardiology, Tokai University, Isehara, Japan.ORCID 0000-0003-4562-7141
Tomokazu FukushimaDepartment of Emergency Care Medicine, Tokai University, Isehara, Japan.
Atsushi UehataDepartment of Emergency Care Medicine, Tokai University, Isehara, Japan.
Chiemi NishikawaDepartment of Emergency Care Medicine, Tokai University, Isehara, Japan.
Seiji MoritaDepartment of Emergency Care Medicine, Tokai University, Isehara, Japan.
Yoshihide NakagawaDepartment of Emergency Care Medicine, Tokai University, Isehara, Japan.
Tsutomu MurakamiDepartment of Cardiology, Tokai University, Isehara, Japan.
Koichiro YoshiokaDepartment of Cardiology, Tokai University, Isehara, Japan.
Yuji IkariDepartment of Cardiology, Tokai University, Isehara, Japan.ORCID 0000-0001-5686-4324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 71-year-old male patient reported to our hospital with anaphylactic shock, and the following two issues were focused in this case. First, he was resistant to adrenaline because of taking beta-blocker, and shock was repeated until glucagon administration was initiated. Second, he developed acute coronary syndrome. Two mechanisms contributing to Kounis syndrome were differentiated: 1) adrenaline induced coronary spasm and platelet activation or 2) a mismatch between oxygen supply and demand due to an allergic reaction. Beta-blocker therapy was discontinued because his cardiac function was preserved. Secondary preventive beta-blockers in recovering myocardial infarction with severe anaphylaxis history should be carefully considered.

Indexed as

AnaphylaxisKounis SyndromeMyocardial InfarctionAgedElectrocardiographyEpinephrineHumansMaleEpinephrineadrenalineanaphylaxisbeta-blockersglucagonKounis syndrome

Identifiers

PMID33783917
PMCPMC8293598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.