Evidence map›Paper›PMID 33783846›Full record

Trial reportJournal of advanced nursing2021

Efficacy of a combination of hypnosis and transcutaneous electrical nerve stimulation for chronic non-cancer pain: A randomized controlled trial.

Louise Tonye-Geoffroy, Stéphanie Mauboussin Carlos, Sophie Tuffet, Hélène Fromentin, Laurence Berard, Judith Leblanc, Françoise Laroche

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of advanced nursing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01944150 (Interest of the Association of Two Complementary Techniques, Hypnosis and Transcutaneous Electrical Nerve Stimulation in the Treatment of Chronic Non-cancer Pain, Nociceptive and / or Neuropathic Pain), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01944150 nacompletednot on this map

Interest of the Association of Two Complementary Techniques, Hypnosis and Transcutaneous Electrical Nerve Stimulation in the Treatment of Chronic Non-cancer Pain, Nociceptive and / or Neuropathic Pain: Randomized Trial

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2013 to 2017Enrolled72ConditionsLimbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back PainArmsTranscutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Louise Tonye-GeoffroyAssistance Publique - Hôpitaux de Paris (AP-HP), Pain Department of Saint-Antoine University Hospital and Medical University Sorbonne, Hôpital Saint-Antoine, Paris, France.
Stéphanie Mauboussin CarlosAssistance Publique - Hôpitaux de Paris (AP-HP), Pain Department of Saint-Antoine University Hospital and Medical University Sorbonne, Hôpital Saint-Antoine, Paris, France.ORCID https://orcid.org/0000-0002-6246-0817
Sophie TuffetAssistance Publique - Hôpitaux de Paris (AP-HP), AP-HP.Sorbonne Université, Clinical Research Unit of East of Paris (URC-Est), Paris, France.
Hélène FromentinAssistance Publique - Hôpitaux de Paris (AP-HP), AP-HP.Sorbonne Université, Clinical Research Center of East of Paris (CRC-Est), Paris, France.
Laurence BerardAssistance Publique - Hôpitaux de Paris (AP-HP), AP-HP.Sorbonne Université, Clinical Research Platform of East of Paris (URC-Est/CRC-Est), Paris, France.
Judith LeblancAssistance Publique - Hôpitaux de Paris (AP-HP), AP-HP.Sorbonne Université, Clinical Research Center of East of Paris (CRC-Est), Paris, France.ORCID https://orcid.org/0000-0002-0323-6671
Françoise LarocheAssistance Publique - Hôpitaux de Paris (AP-HP), Pain Department of Saint-Antoine University Hospital and Medical University Sorbonne, Hôpital Saint-Antoine, Paris, France.
Sorbonne Université · FRInserm · FR

Funding

Programme Hospitalier de Recherche Infirmière et Paramédicale - PHRIP 2012 (Ministère de la Santé, No. PHRI120049)
6 · The paper itself

Abstract

backgroundChronic non-cancer pain, which persists for at least three months, seriously affects quality of life. Chronic non-cancer pain patients are usually managed by a multidisciplinary team using pharmacological and non-pharmacological strategies. Nurses perform transcutaneous electrical nerve stimulation (TENS) and hypnosis, which are widely used in France for the treatment of chronic pain in pain departments.

objectiveTo assess pain relief at three months, comparing a simultaneous combination of hypnosis and TENS (intervention) with TENS alone (control).

designRandomized controlled trial.

methodsPatients aged 18-80 years, suffering from chronic peripheral neuropathic and/or nociceptive non-cancer pain were included (September 2013 to May 2017) and followed for six months. The primary outcome was the pain intensity difference (by visual analog scale score) between month 3 and baseline. The secondary outcomes, assessed at months 3 and 6, were SF36 score, analgesics consumption and number of TENS sessions performed at home (last seven days).

resultsSeventy-two patients were included, suffering from a combination of chronic non-cancer nociceptive and neuropathic pain, with a mean pain intensity of about sixty out of a hundred. The results show an important pain reduction (forty percent) in both groups at 3 months. No significant difference was observed between the control and intervention groups. Similarly, SF36 score, change in analgesic intake and patient compliance did not differ significantly between groups.

conclusionsThis is the first randomized controlled study showing a decrease of pain intensity and a high level of compliance with transcutaneous electrical nerve stimulation alone or associated to hypnosis. The combination does not seem to be more efficient than transcutaneous electrical nerve stimulation alone. Chronic non-cancer pain remains a major issue and a substantial proportion of patients do not appear to benefit from interventions. IMPACT: This study increases our understanding of the combination of two non-pharmacological methods in chronic non-cancer pain patients. The combination of the two non-pharmacological strategies did not appear to be more efficient than one alone. Further research on non-pharmacological treatments targeting to patient's characteristics are needed to find appropriate strategies in patients with complex multidimensional pain conditions. Clinical Trial Number: NCT01944150 (Sept. 17, 2013).

Indexed as

Chronic PainHypnosisTranscutaneous Electric Nerve StimulationAnalgesics, OpioidFranceHumansQuality of LifeAnalgesics, Opioidchronic non-cancer painhypnosisnurse caringtranscutaneous electrical nerve stimulation

Identifiers

PMID33783846
PMCPMC8251595
OpenAlexW3146865329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.