ArticleThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry2021
Genome-wide association study of suicidal behaviour severity in mood disorders.
Article in The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genome-wide association study meta-analysis of suicide death and suicidal behavior.Molecular psychiatry · 2023Pooled it
- Genetics and epigenetics of self-injurious thoughts and behaviors: Systematic review of the suicide literature and methodological considerations.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2022Pooled it
- Neurostructural Correlates of Polygenic Risk for Coronary Artery Disease in Relation to Youth Bipolar Disorder.Bipolar disorders · 2025Article
- 'Unravelling the shared genetic architecture between suicidality and subcortical brain volume: a genome-wide association study'.Acta neuropsychiatrica · 2025Article
- Using the Strategy of Genome-Wide Association Studies to Identify Genetic Markers of Suicidal Behavior: A Narrative Review.Consortium psychiatricum · 2024Review
- Mu opioid receptor gene variant modulates subjective response to smoked cannabis.American journal of translational research · 2022Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
objectiveSuicide is a major public health problem and it has a prominent genetic component. We performed a genome-wide association study (GWAS) of suicidal behaviour severity.
methodsSuicide behaviour severity was assessed within the Schedules for Clinical Assessment in Neuropsychiatry in our mood disorder sample (
resultsWe did not detect genome-wide significant findings at the single-marker or gene level. We report a number of suggestive single-marker and gene-based findings. Our polygenic risk score analyses did not yield significant findings with these phenotypes.
conclusionsLarger sample sizes are required to detect moderate effects.
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Registered trials
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