Evidence map›Paper›PMID 33783283›Full record

ArticleAnnals of medicine2021

Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling.

Yixuan Qiu, Jiaming Yu, Yi Li, Fan Yang, Huiyuan Yu, Mengjuan Xue, Fan Zhang, Xin Jiang, Xueying Ji, Zhijun Bao

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Journal of microbiology and biotechnology · 2026
    Article
  5. The gut as a central hub for multi-organ crosstalk in aging.Cellular and molecular life sciences : CMLS · 2026
    Review
  6. Review
  7. Cancer cachexia: molecular basis and therapeutic advances.Signal transduction and targeted therapy · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
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  17. Article
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yixuan QiuDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.ORCID 0000-0003-0481-6923
Jiaming YuDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Yi LiDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Fan YangDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Huiyuan YuDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Mengjuan XueDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Fan ZhangDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Xin JiangDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Xueying JiDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Zhijun BaoDepartment of Gerontology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Fudan University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBile Acids and SaltsDisease Models, AnimalDown-RegulationDysbiosisFibroblast Growth FactorsGastrointestinal MicrobiomeIntestinal MucosaIntestinesMiceMice, Inbred C57BLMuscle, SkeletalMuscular AtrophyReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearAnti-Bacterial AgentsBile Acids and Saltsfibroblast growth factor 15, mouseFibroblast Growth FactorsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearRNA, Ribosomal, 16Sbile acidFGF15/19FXRGut microbiotaskeletal muscle

Identifiers

PMID33783283
PMCPMC8018554
OpenAlexW3139610313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.