Evidence map›Paper›PMID 33782651›Full record

ReviewBeni-Suef University journal of basic and applied sciences2021

Perspectives on plant flavonoid quercetin-based drugs for novel SARS-CoV-2.

Manjesh Saakre, Deepu Mathew, V Ravisankar

Open access · diamondAbstract readReview
In one paragraph

Review in Beni-Suef University journal of basic and applied sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Bioactive Compounds ofInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Arabian journal of chemistry · 2023
    Article
  9. Article
  10. Inhibitory mechanism of quercetin onFrontiers in microbiology · 2023
    Article
  11. Natural flavonols: actions, mechanisms, and potential therapeutic utility for various diseases.Beni-Suef University journal of basic and applied sciences · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Manjesh SaakreNational Institute for Plant Biotechnology, Indian Agricultural Research Institute, Pusa, New Delhi, 110 012 India.
Deepu MathewBioinformatics Centre, Kerala Agricultural University, Thrissur, 680 656 India.ORCID 0000-0002-2941-1060
V RavisankarBioinformatics Centre, Kerala Agricultural University, Thrissur, 680 656 India.
Kerala Agricultural University · INNational Research Centre on Plant Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe world pandemic COVID-19 caused by SARS-CoV-2 is currently claiming thousands of lives. Flavonoids abundantly present in the fruits and vegetables, especially quercetin, are shown to have antiviral activities. MAIN TEXT: This paper reviews the capability of the plant flavonoid quercetin to fight the novel coronavirus and the possibility for drug development based on this. The mode of action explaining the known pathways through which this molecule succeeds in the antiviral activity, action of quercetin on SARS-CoV-2 main protease 3CL

conclusionThe antiviral properties of flavonoid and the molecular mechanisms involved are reviewed. Further, proof for this concept is given by docking of key proteins from SARS-CoV-2 with quercetin. GRAPHICAL ABSTRACT:

Indexed as

3CLproAntiviralCOVID-19Drug designmiRNAPhytomedicineZinc

Identifiers

PMID33782651
PMCPMC7989718
OpenAlexW3140823273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.