ArticleInternational cancer conference journal2021
Oncocytic variant, a novel subtype of chromophobe renal cell carcinoma: a report of two cases and a literature review.
Article in International cancer conference journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- Rare tumor subtypes diagnosed by molecular analysis.International cancer conference journal · 2021Article
- Renal oncocytoma with prominent xanthomatous reaction. A rare histopathological variant of oncocytoma.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
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9 authors at 4 institutions in 1 country.
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Abstract
A novel variant of chromophobe renal cell carcinoma showing an oncocytic phenotype is proposed. Two new cases of this rare entity are presented and discussed along with six previous cases from our colleagues. A 76-year-old man and a 78-year-old man had a 3.4-cm and a 3.2-cm-diameter renal mass, respectively. On histopathological examination of surgical specimens, uniform eosinophilic cuboidal cells without a perinuclear halo growing in a tubular pattern were seen, and differential diagnosis from oncocytoma was necessary. Immunohistochemical staining for cytokeratin 7 and E-cadherin showed diffusely positive patterns in both, as in the previous reports. Although monosomy of chromosomes 7, 10, 13, and 17 was commonly observed in the previous reports, gains of chromosome 19 were observed in the two present cases. Immunohistochemical and cytogenetic approaches lead to exclusion of oncocytoma and the diagnosis of an oncocytic variant of chromophobe renal cell carcinoma.
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