ArticleNature neuroscience2021
An inhibitory hippocampal-thalamic pathway modulates remote memory retrieval.
Article in Nature neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Integrating optogenetic fMRI and spatial transcriptomics to reveal circuit-specific gene signatures in fronto- and hippo-thalamic networks.Nature communications · 2026Article
- Pathological tau alters head direction signaling and induces spatial disorientation.Cell reports · 2025Article
- A dorsal subiculum-medial mammillary body pathway for spatial memory.Molecular psychiatry · 2025Article
- Long-Term Memory Engrams From Development to Adulthood.Hippocampus · 2025Review
- Article
- FNDC5/irisin mediates the protective effects of Innovative theta-shaking exercise on mouse memory.Heliyon · 2024Article
- Review
- Memory Storage in Distributed Engram Cell Ensembles.Advances in neurobiology · 2024Review
- Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory.Molecular psychiatry · 2023Review
- Article
- Article
- Anteromedial Thalamus Gates the Selection & Stabilization of Long-Term Memories.bioRxiv : the preprint server for biology · 2023Article
- Exploring the memory: existing activity-dependent tools to tag and manipulate engram cells.Frontiers in cellular neuroscience · 2023Review
- The thalamic reuniens is associated with consolidation of non-spatial memory too.Frontiers in behavioral neuroscience · 2023Article
- Time to retire the serial Papez circuit: Implications for space, memory, and attention.Neuroscience and biobehavioral reviews · 2022Review
- The anterior thalamic nuclei: core components of a tripartite episodic memory system.Nature reviews. Neuroscience · 2022Review
- Thalamo-hippocampal pathway regulates incidental memory capacity in mice.Nature communications · 2022Article
- Anterior thalamic circuits crucial for working memory.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Remote contextual fear retrieval engages activity from salience network regions in rats.Neurobiology of stress · 2022Article
- Article
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Authors and funding
6 authors.
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Abstract
Memories are supported by distributed hippocampal-thalamic-cortical networks, but the brain regions that contribute to network activity may vary with memory age. This process of reorganization is referred to as systems consolidation, and previous studies have examined the relationship between the activation of different hippocampal, thalamic, and cortical brain regions and memory age at the time of recall. While the activation of some brain regions increases with memory age, other regions become less active. In mice, here we show that the active disengagement of one such brain region, the anterodorsal thalamic nucleus, is necessary for recall at remote time-points and, in addition, which projection(s) mediate such inhibition. Specifically, we identified a sparse inhibitory projection from CA3 to the anterodorsal thalamic nucleus that becomes more active during systems consolidation, such that it is necessary for contextual fear memory retrieval at remote, but not recent, time-points post-learning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.