Evidence map›Paper›PMID 33782460›Full record

ArticleScientific reports2021

Camel whey protein hydrolysates induced G2/M cellcycle arrest in human colorectal carcinoma.

Chandraprabha Murali, Priti Mudgil, Chee-Yuen Gan, Hamadeh Tarazi, Raafat El-Awady, Youssef Abdalla, Amr Amin, Sajid Maqsood

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Camel Milk in Skin Cancer Therapeutics: AnAnti-cancer agents in medicinal chemistry · 2026
    Article
  6. Immune Enhancement of FermentedMolecules (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Bioactive potency of extracts fromBiomedical reports · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Current issues in molecular biology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Chandraprabha MuraliBiology Department, College of Science, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Priti MudgilFood, Nutrition and Health Department, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE.
Chee-Yuen GanAnalytical Biochemistry Research Centre (ABrC), University Innovation Incubator Building, sains@usm campus, Universiti Sains Malaysia, 11900, Bayan Lepas, Penang, Malaysia.
Hamadeh TaraziCollege of Pharmacy, University of Sharjah, Sharjah, UAE.
Raafat El-AwadyCollege of Pharmacy, University of Sharjah, Sharjah, UAE.
Youssef AbdallaDepartment of Kinesiology, Michigan State University, East Lansing, MI, 48824, USA.
Amr AminBiology Department, College of Science, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE. a.amin@uaeu.ac.ae.
Sajid MaqsoodFood, Nutrition and Health Department, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, UAE. sajid.m@uaeu.ac.ae.
United Arab Emirates University · AEUniversity of Sharjah · AEMichigan State University · USUniversiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Camel milk has been gaining immmense importance due to high nutritious value and medicinal properties. Peptides from milk proteins is gaining popularity in various therapeutics including human cancer. The study was aimed to investigate the anti-cancerous and anti-inflammatory properties of camel whey protein hydrolysates (CWPHs). CWPHs were generated at three temperatures (30 ℃, 37 ℃, and 45 ℃), two hydrolysis timepoints (120 and 360 min) and with three different enzyme concentrations (0.5, 1 and 2 %). CWPHs demonstrated an increase in anti-inflammatory effect between 732.50 (P-6.1) and 3779.16 (P-2.1) µg Dicolfenac Sodium Equivalent (DSE)/mg protein. CWPHs (P-4.3 & 5.2) inhibited growth of human colon carcinoma cells (HCT116) with an IC

Indexed as

AnimalsCamelusCell DivisionColorectal NeoplasmsG2 PhaseHumansWhey ProteinsWhey Proteins

Identifiers

PMID33782460
PMCPMC8007640
OpenAlexW3149465127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.