ArticleNature communications2021
Reversed evolution of grazer resistance to cyanobacteria.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Rapid temporal adaptation structures tolerance to toxic cyanobacteria in a natural population of the water fleaEvolution letters · 2025Article
- Transgenerational epigenetic inheritance increases trait variation but is not adaptive.Evolution; international journal of organic evolution · 2025Article
- Experimental ecology and the balance between realism and feasibility in aquatic ecosystems.Nature communications · 2025Review
- A test for microbiome-mediated rescue via host phenotypic plasticity inProceedings. Biological sciences · 2025Article
- Article
- Biomarkers and immunotherapy in endometrial cancer: mechanisms and clinical applications.Frontiers in immunology · 2025Review
- Intraspecific diversity is critical to population-level risk assessments.Scientific reports · 2024Article
- A test for microbiome-mediated rescue via host phenotypic plasticity inbioRxiv : the preprint server for biology · 2024Article
- The genome-wide signature of short-term temporal selection.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Transgenerational epigenetic inheritance increases trait variation but is not adaptive.bioRxiv : the preprint server for biology · 2024Article
- Intraspecific genetic variation is critical to robust toxicological predictions of aquatic contaminants.bioRxiv : the preprint server for biology · 2023Article
- Review
- A sterol-mediated gleaner-opportunist trade-off underlies the evolution of grazer resistance to cyanobacteria.Proceedings. Biological sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Exploring the capability of organisms to cope with human-caused environmental change is crucial for assessing the risk of extinction and biodiversity loss. We study the consequences of changing nutrient pollution for the freshwater keystone grazer, Daphnia, in a large lake with a well-documented history of eutrophication and oligotrophication. Experiments using decades-old genotypes resurrected from the sediment egg bank revealed that nutrient enrichment in the middle of the 20th century, resulting in the proliferation of harmful cyanobacteria, led to the rapid evolution of grazer resistance to cyanobacteria. We show here that the subsequent reduction in nutrient input, accompanied by a decrease in cyanobacteria, resulted in the re-emergence of highly susceptible Daphnia genotypes. Expression and subsequent loss of grazer resistance occurred at high evolutionary rates, suggesting opposing selection and that maintaining resistance was costly. We provide a rare example of reversed evolution of a fitness-relevant trait in response to relaxed selection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.