Evidence map›Paper›PMID 33782153›Full record

ArticleInfection and immunity2021

Sialic Acid Protects Nontypeable Haemophilus influenzae from Natural IgM and Promotes Survival in Murine Respiratory Tract.

Mary Darby Jackson, Sandy M Wong, Brian J Akerley

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. AASM case reports · 2025
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mary Darby JacksonDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA.ORCID 0000-0002-4447-1424
Sandy M WongDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Brian J AkerleyDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA bakerley@umc.edu.ORCID 0000-0002-8142-7035
University of Mississippi Medical Center · US

Funding

Mechanisms of Haemophilus influenzae pathogenesis in the lungR01AI095740 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AKERLEY, BRIAN, SHEN, HAO · 2012 to 2016
$1.8M
NIAID NIH HHS R01 AI095740
6 · The paper itself

Abstract

Nontypeable

Indexed as

AnimalsAntibodies, BacterialDisease Models, AnimalHaemophilus InfectionsHaemophilus influenzaeImmunoglobulin MLipopolysaccharidesMiceMicrobial ViabilityN-Acetylneuraminic AcidRespiratory Tract InfectionsAntibodies, BacterialImmunoglobulin Mlipid-linked oligosaccharidesLipopolysaccharidesN-Acetylneuraminic Acidcomplement resistanceHaemophilus influenzaeIgMimmune evasionlipooligosaccharidelung infectionmouse modelnatural antibodyNTHisialic acid

Identifiers

PMID33782153
PMCPMC8315930
OpenAlexW3148171397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.