Evidence map›Paper›PMID 33782130›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The myosin II coiled-coil domain atomic structure in its native environment.

Hamidreza Rahmani, Wen Ma, Zhongjun Hu, Nadia Daneshparvar, Dianne W Taylor, J Andrew McCammon, Thomas C Irving, Robert J Edwards, Kenneth A Taylor

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Structural basis of nonmuscle myosin-2 autoinhibition mechanisms.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Review
  6. Two Forms of Thick Filament in the Flight Muscle ofInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. Structure, regulation, and mechanisms of nonmuscle myosin-2.Cellular and molecular life sciences : CMLS · 2024
    Review
  10. Article
  11. Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. Structure of theInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
  17. John Squire and the myosin thick filament structure in muscle.Journal of muscle research and cell motility · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hamidreza RahmaniInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380.ORCID 0000-0003-0222-6989
Wen MaDepartment of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0002-1123-5273
Zhongjun HuInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380.ORCID 0000-0003-0431-0834
Nadia DaneshparvarInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380.ORCID 0000-0002-5661-1228
Dianne W TaylorInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380.ORCID 0000-0002-2033-4978
J Andrew McCammonDepartment of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-3065-1456
Thomas C IrvingDepartment of Biological Sciences, Illinois Institute of Technology, Chicago, IL 60616.ORCID 0000-0003-4848-3323
Robert J EdwardsDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27607.ORCID 0000-0003-4446-1194
Kenneth A TaylorInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380; ktaylor@fsu.edu.ORCID 0000-0001-9594-8360

Funding

Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
THEORY OF BIOMOLECULAR DIFFUSIONR01GM031749 · NIGMS · UNIVERSITY OF HOUSTON · PI HUBER, GARY ALEXANDER, MCCAMMON, JAMES ANDREW · 1985 to 2022
$7.8M
EM STUDIES ON MUSCLER01GM030598 · NIGMS · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 1985 to 2020
$4.9M
The Southeastern Consortium for Microscopy of MacroMolecular MachinesU24GM116788 · NIGMS · FLORIDA STATE UNIVERSITY · PI AGBANDJE-MCKENNA, MAVIS, BULLITT, ESTHER · 2016 to 2020
$4.6M
MYOFIBRILLAR STRUCTURE OF STRIATED MUSCLER01AR014317 · NIAMS · DUKE UNIVERSITY · PI EDWARDS, ROBERT JON · 1986 to 2016
$2.1M
Zeiss 510 Multiphoton/single-photon Confocal MicroscopeS10RR020981 · NCRR · CORNELL UNIVERSITY ITHACA · PI ZIPFEL, WARREN R · 2005 to 2005
$500k
NCRR NIH HHS S10 RR020981NIAMS NIH HHS R01 AR014317NIGMS NIH HHS P41 GM103622NIGMS NIH HHS R01 GM030598NIGMS NIH HHS R01 GM031749NIGMS NIH HHS U24 GM116788
6 · The paper itself

Abstract

The atomic structure of the complete myosin tail within thick filaments isolated from

Indexed as

AnimalsCryoelectron MicroscopyHemipteraInsect ProteinsMolecular Dynamics SimulationMuscle, SkeletalMyosin Type IIProtein Conformation, alpha-HelicalInsect ProteinsMyosin Type IIalpha helix coiled coilcryo-electron microscopyfilamentinvertebratestriated muscle

Identifiers

PMID33782130
PMCPMC8040620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.