Evidence map›Paper›PMID 33782125›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

ZYP1 is required for obligate cross-over formation and cross-over interference in

Martin G France, Janina Enderle, Sarah Röhrig, Holger Puchta, F Chris H Franklin, James D Higgins

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 127 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Breeding better crops: lessons from the homologous recombination pathway.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  5. Review
  6. Structure and function of the synaptonemal complex.The Journal of cell biology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Multi-step implementation of meiotic crossover patterning.bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Improved synapsis dynamics accompany meiotic stability inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. The histone variant H2A.W restricts heterochromatic crossovers inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Martin G FranceDepartment of Genetics and Genome Biology, University of Leicester, LE1 7RH Leicester, United Kingdom.
Janina EnderleBotanical Institute, Molecular Biology and Biochemistry, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.ORCID 0000-0002-7016-0064
Sarah RöhrigBotanical Institute, Molecular Biology and Biochemistry, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.
Holger PuchtaBotanical Institute, Molecular Biology and Biochemistry, Karlsruhe Institute of Technology, Karlsruhe 76131, Germany.ORCID 0000-0003-1073-8546
F Chris H FranklinSchool of Biosciences, University of Birmingham, B15 2TT Birmingham, United Kingdom.ORCID 0000-0003-3507-722X
James D HigginsDepartment of Genetics and Genome Biology, University of Leicester, LE1 7RH Leicester, United Kingdom; jh555@leicester.ac.uk.ORCID 0000-0001-6027-8678
Karlsruhe Institute of Technology · DEUniversity of Leicester · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is characterized by the coordinated installation of transverse filament proteins between two lateral elements and is required for wild-type levels of crossing over and meiotic progression. We have generated null mutants of the duplicated

Indexed as

Crossing Over, GeneticArabidopsisArabidopsis ProteinsMeiosisSynaptonemal ComplexArabidopsis ProteinsZYP1a protein, ArabidopsisZYP1b protein, Arabidopsiscross-over interferencemeiosisrecombinationsynaptonemal complex

Identifiers

PMID33782125
PMCPMC8040812
OpenAlexW3145568833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.