Evidence map›Paper›PMID 33782115›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies.

Jonathan D Schaefer, Nayla R Hamdi, Stephen M Malone, Scott Vrieze, Sylia Wilson, Matt McGue, William G Iacono

Open access · greenAbstract readTwin Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cannabis and Cannabinoid Signaling: Research Gaps and Opportunities.The Journal of pharmacology and experimental therapeutics · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Consequences of adolescent drug use.Translational psychiatry · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Comparative Pharmacokinetics of ΔCannabis and cannabinoid research · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jonathan D SchaeferInstitute of Child Development, University of Minnesota, Minneapolis, MN 55455; schae567@umn.edu.ORCID 0000-0003-4112-9268
Nayla R HamdiNorthwest Metro VA Clinic, Minneapolis Veterans Affairs Health Care System, Ramsey, MN 55303.ORCID 0000-0003-1543-1850
Stephen M MaloneDepartment of Psychology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0001-9201-7616
Scott VriezeDepartment of Psychology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0003-3861-7930
Sylia WilsonInstitute of Child Development, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0003-0144-524X
Matt McGueDepartment of Psychology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-5580-1433
William G IaconoDepartment of Psychology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-3194-3090
University of Minnesota · USMinneapolis VA Health Care System · US

Funding

The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsR01DA042755 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Jarrod Martin Ellingson, SOO H RHEE · 2017 to 2026
$9.9M
Twin Family Study of Vulnerability to Substance AbuseR37DA005147 · NIDA · UNIVERSITY OF MINNESOTA · PI IACONO, WILLIAM G. · 2009 to 2018
$6.4M
INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32MH015755 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Megan R Gunnar · 1985 to 2026
$5.9M
Adolescent drinking and midlife outcomes: A prospective cotwin control studyR37AA009367 · NIAAA · UNIVERSITY OF MINNESOTA · PI MCGUE, MATTHEW K. · 2016 to 2024
$5.4M
Adult consequences of youth substance use: Twin study enriched for SUD riskR01DA036216 · NIDA · UNIVERSITY OF MINNESOTA · PI IACONO, WILLIAM G. · 2013 to 2017
$3.2M
Deep Sequencing, Phenotyping, and Imputation in Large-Scale Biobanks: A Novel and Cost-Effective Framework to Identify Rare Mutations Associated with AddictionR01DA044283 · NIDA · UNIVERSITY OF MINNESOTA · PI ALBERT, FRANK WOLFGANG, VRIEZE, SCOTT IAN · 2019 to 2024
$3.2M
Genetic Association Meta-Analyses of Smoking and Drinking for the Sequencing AgeR01DA037904 · NIDA · UNIVERSITY OF MINNESOTA · PI VRIEZE, SCOTT IAN · 2015 to 2019
$2.4M
Brain Deviation Preceding Substance Use: An Offspring of Co-Twin Control StudyK01DA037280 · NIDA · UNIVERSITY OF MINNESOTA · PI WILSON, SYLIA · 2015 to 2019
$764k
Neural outcomes of moderating alcohol use in early adulthoodR21AA026919 · NIAAA · UNIVERSITY OF MINNESOTA · PI MALONE, STEPHEN MATTHEW · 2019 to 2020
$497k
Co-Twin Control Analysis of Effects of Alcohol on Brain Morphometry: Disentangling Cause From ConsequenceR21AA026632 · NIAAA · UNIVERSITY OF MINNESOTA · PI WILSON, SYLIA · 2018 to 2019
$477k
NIAAA NIH HHS R21 AA026632NIAAA NIH HHS R21 AA026919NIAAA NIH HHS R37 AA009367NIDA NIH HHS K01 DA037280NIDA NIH HHS R01 DA036216NIDA NIH HHS R01 DA037904NIDA NIH HHS R01 DA042755NIDA NIH HHS R01 DA044283NIDA NIH HHS R37 DA005147NIMH NIH HHS T32 MH015755
6 · The paper itself

Abstract

Observational studies have linked cannabis use to an array of negative outcomes, including psychiatric symptoms, cognitive impairment, and educational and occupational underachievement. These associations are particularly strong when cannabis use occurs in adolescence. Nevertheless, causality remains unclear. The purpose of the present study was thus to examine associations between prospectively assessed adolescent cannabis use and young-adult outcomes (psychiatric, cognitive, and socioeconomic) in three longitudinal studies of twins (

Indexed as

Educational StatusEmploymentAdolescentAdultCannabisChildCognitionHumansLongitudinal StudiesMarijuana UseMental DisordersMinnesotaYoung Adultadolescencecannabiseducationmarijuanatwin

Identifiers

PMID33782115
PMCPMC8040790
OpenAlexW3141994901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.